Tumor Immunology and Cancer Vaccines 1st edition by Samir Khleif – Ebook PDF Instant Download/Delivery: 0387275451 , 9780387275451
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Product details:
ISBN 10: 0387275451
ISBN 13: 9780387275451
Author: Samir Khleif
It all started with an observation. Edward Jenner, an English physician, observed that milkmaids who contracted cowpox were rarely victims of smallpox epidemic, a disease that in?icted a heavy toll on humankind with an estimate of 500 million victimsworldwide.In1796,Jennerinoculatedtheextracted?uidfromblistersonthe handofamilkmaidwhowasinfectedwithcowpoxintothearman8yearoldpeasant boy. After the boy recovered from a mild illness caused by this inoculation, Jenner exposed him to smallpox and to his delight the boy did not develop the disease. He published his work in 1798 in three publications titled “Vaccination Against smallpox”, where the term vaccination is derived from the Latin word “vacca” meaning cow. Jenner was recognized to be the father of modern immunology, and hisworkmarkedthecommencementofanewdawninmedicinethatledtothe1979 declaration by the World Health Organization (WHO) of the global eradication of smallpox. By the beginning of the 20th century, vaccines for typhoid fever, rabies, polio, plaque and diphtherias were in use, and nowadays we are equipped with effectivevaccinesagainstmorethan20infectiousdiseasessuchasmeningitis,rubella, whooping cough, rabies, and hepatitis B among others.
Tumor Immunology and Cancer Vaccines 1st Table of contents:
Part One: Fundamentals of Tumor Immunology
Chapter 1. Basic Tumor Immunology
Chapter 2. Antigen Processing and Presentation
Chapter 3. Antigen Recognition and T-Cell Biology
Chapter 4. Mechanisms of Tumor Evasion
Chapter 5. Tumor Antigens and Tumor Antigen Discovery
Part Two: Cancer Vaccine Development
Chapter 6. Cancer Vaccine Development
Chapter 7. Peptide Vaccines Against Cancer
Chapter 8. DNA Vaccination in Immunotherapy of Cancer
Chapter 9. Antibody-Inducing Polyvalent Cancer Vaccines
Chapter 10. Dendritic Cell-Based Vaccines for Cancer Therapy
Chapter 11. Undefined-Antigen Vaccines
Chapter 12. Cancer Vaccines in Combination with Multimodality Therapy
Chapter 13. Vaccine-Enhancing Strategies
Chapter 14. Cytokine Therapy for Cancer: Antigen Presentation
Chapter 15. Tinkering with Nature: The Tale of Optimizing Peptide-Based Cancer Vaccines
Chapter 16. Tumor Immunology and Cancer Vaccines
Part Three: Clinical Trials and Immune Monitoring
Chapter 17. Clinical Trials Design
Chapter 18. Clinical Trial Designs for Therapeutic Cancer Vaccines
Chapter 19. Clinical Trial Design and Regulatory Issues for Therapeutic Cancer Vaccines
Chapter 20. Immune Monitoring
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Tags: Samir Khleif, Tumor Immunology, Cancer Vaccines