Basic Immunology Functions and Disorders of the Immune System 6th Editon by Abul Abbas, Andrew Lichtman, Shiv Pillai ISBN 0323549438 9780323549431

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ISBN 10: 0323549438
ISBN 13: 9780323549431
Author: Abul K. Abbas; Andrew H. Lichtman; Shiv Pillai

Meticulously reviewed and updated for today’s medical students, Basic Immunology, 6th Edition, is a concise text expertly written by the same distinguished author team as the best-selling, comprehensive text, Cellular and Molecular Immunology. This focused, easy-to-understand volume uses full-color illustrations and clinical images, useful tables, and practical features such as Summary Point boxes, end-of-chapter review questions, glossary terms, and clinical cases—all designed to help students master this complex topic in the most efficient, effective manner possible.

Basic Immunology Functions and Disorders of the Immune System 6th Table of contents:

1. Introduction to the Immune System: Nomenclature, General Properties, and Components

Innate and Adaptive Immunity

Types of Adaptive Immunity

Properties of Adaptive Immune Responses

Cells of the Adaptive Immune System

Tissues of the Immune System

Summary

Review Questions

2. Innate Immunity: The Early Defense Against Infections

General Features and Specificity of Innate Immune Responses

Cellular Receptors for Microbes and Damaged Cells

Components of Innate Immunity

Innate Immune Reactions

Role of Innate Immunity in Stimulating Adaptive Immune Responses

Summary

Review Questions

3. Antigen Capture and Presentation to Lymphocytes: What Lymphocytes See

Antigens Recognized by T Lymphocytes

Capture of Protein Antigens by Antigen-Presenting Cells

Structure and Function of Major Histocompatibility Complex Molecules

Processing and Presentation of Protein Antigens

Functions of Antigen-Presenting Cells in Addition to Antigen Display

Antigen Recognition by B Cells and Other Lymphocytes

Summary

Review Questions

4. Antigen Recognition in the Adaptive Immune System: Structure of Lymphocyte Antigen Receptors and Development of Immune Repertoires

Antigen Receptors of Lymphocytes

Development of B and T Lymphocytes

Summary

Review Questions

5. T Cell–Mediated Immunity: Activation of T Lymphocytes

Phases of T Cell Responses

Antigen Recognition and Costimulation

Biochemical Pathways of T Cell Activation

Functional Responses of T Lymphocytes to Antigen and Costimulation

Migration of T Lymphocytes in Cell-Mediated Immune Reactions

Summary

Review Questions

6. Effector Mechanisms of T Cell–Mediated Immunity: Functions of T Cells in Host Defense

Types of T Cell–Mediated Immune Reactions

Development and Functions of CD4+ Effector T Lymphocytes

Differentiation and Functions of CD8+ Cytotoxic T Lymphocytes

Resistance of Pathogenic Microbes to Cell-Mediated Immunity

Summary

Review Questions

7. Humoral Immune Responses: Activation of B Lymphocytes and Production of Antibodies

Phases and Types of Humoral Immune Responses

Stimulation of B Lymphocytes by Antigen

Functions of Helper T Lymphocytes in Humoral Immune Responses

Antibody Responses to T-Independent Antigens

Regulation of Humoral Immune Responses: Antibody Feedback

Summary

Review Questions

8. Effector Mechanisms of Humoral Immunity: Elimination of Extracellular Microbes and Toxins

Properties of Antibodies that Determine Effector Function

Neutralization of Microbes and Microbial Toxins

Opsonization and Phagocytosis

Antibody-Dependent Cellular Cytotoxicity

Immunoglobulin E– and Eosinophil/Mast Cell–Mediated Reactions

The Complement System

Functions of Antibodies at Special Anatomic Sites

Evasion of Humoral Immunity by Microbes

Vaccination

Summary

Review Questions

9. Immunologic Tolerance and Autoimmunity: Self–Nonself Discrimination in the Immune System and Its Failure

Immunologic Tolerance: General Priniciples and Significance

Central T Lymphocyte Tolerance

Peripheral T Lymphocyte Tolerance

B Lymphocyte Tolerance

Tolerance to Commensal Microbes and Fetal Antigens

Autoimmunity

Summary

Review Questions

10. Immunology of Tumors and Transplantation: Immune Responses to Cancer Cells and Normal Foreign Cells

Immune Responses Against Tumors

Immune Responses Against Transplants

Summary

Review Questions

11. Hypersensitivity: Disorders Caused by Immune Responses

Types of Hypersensitivity Reactions

Immediate Hypersensitivity

Diseases Caused by Antibodies Specific for Cell and Tissue Antigens

Diseases Caused By Antigen-Antibody Complexes

Diseases Caused by T Lymphocytes

Neuroimmunology: Interactions Between the Immune and Nervous Systems

Summary

Review Questions

12. Congenital and Acquired Immunodeficiencies: Diseases Caused by Defective Immunity

Congenital (Primary) Immunodeficiencies

Acquired (Secondary) Immunodeficiencies

Acquired Immunodeficiency Syndrome

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