Medical Microbiology A Guide to Microbila Infections Pathogenesis Immunity Laboratory Investigation and Control 18th edition by David Greenwood, Michael Barer, Will Irving, Richard Slack 0702051195 9780702051197

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ISBN 10: 0702051195

ISBN 13: 9780702051197

Author: David Greenwood, Michael R. Barer, Will L. Irving, Richard C. B. Slack

Medical Microbiology 18th edition will inform and inspire a new generation of readers. Initial sections cover the basic biology of microbes, infection and immunity and are followed by a systematic review of infective agents, their associated diseases and their control. A final integrating section addresses the essential principles of diagnosis, treatment and management.

Medical Microbiology A Guide to Microbila Infections Pathogenesis Immunity Laboratory Investigation and Control 18th Table of contents:

Chapter 1: Microbial Biology

1.1. Microbiology and Medicine
1.2. An Outline History of Microbiology and Infection
1.3. Micro-organisms and Infection
1.4. Hygiene, Treatment, and Prevention of Infection
1.5. Sources and Spread of Infection
1.6. Recommended Reading
1.7. Websites

Chapter 2: Morphology and Nature of Micro-organisms

2.1. Prokaryotic and Eukaryotic Cells
2.2. Anatomy of the Bacterial Cell
2.3. Bacterial Nucleoid
2.4. Ribosomes
2.5. Cytoplasmic Membrane
2.6. Cell Wall
2.7. Extracellular Polysaccharides: Capsules, Microcapsules, and Loose Slime S-layers
2.8. Flagella and Motility
2.9. Fimbriae and Pili
2.10. Importance of Microbial Surface Structures in Infection
2.11. The Bacterial “Life Cycle”
2.12. Bacterial Spores
2.13. Conidia (Exospores)
2.14. Pleomorphism and Involution
2.15. Spheroplasts, Protoplasts, and L-forms
2.16. The Nature and Composition of Viruses
– 2.16.1. Structure
– 2.16.2. Viral Nucleic Acid
– 2.16.3. Virion Enzymes
– 2.16.4. Viral Proteins
– 2.16.5. Viroids, Defective Viruses, and Prions
2.17. Recommended Reading
2.18. Websites

Chapter 3: Classification, Identification, and Typing of Micro-organisms

3.1. Taxonomy
3.2. Methods of Classification
– 3.2.1. Adansonian or Numerical Classification
– 3.2.2. DNA Composition
– 3.2.3. DNA Homology
– 3.2.4. Ribosomal RNA Sequencing
3.3. Classification in Clinical Practice
– 3.3.1. Protozoa
– 3.3.2. Fungi
– 3.3.3. Bacteria (Actinobacteria, Firmicutes, Proteobacteria, Bacteroidetes, Spirochaetales, Chlamydiae)
– 3.3.4. Viruses
3.4. Identification of Micro-organisms
– 3.4.1. Microscopy
– 3.4.2. Cultural Characteristics
– 3.4.3. Biochemical Reactions
– 3.4.4. Indirect Identification Methods
– 3.4.5. Gene-targeted Analyses
– 3.4.6. Antibody Reactions (Latex Agglutination, Enzyme-linked Immunosorbent Assay, Haemagglutination and Haemadsorption)
– 3.4.7. Fluorescence Microscopy and Immunofluorescence
– 3.4.8. Immuno-polymerase Chain Reaction
3.5. Typing of Bacteria
– 3.5.1. Biotyping
– 3.5.2. Serotyping
– 3.5.3. Phage Typing
– 3.5.4. Bacteriocin Typing
– 3.5.5. Protein Typing
– 3.5.6. Restriction Endonuclease Typing
– 3.5.7. Gene Probe Typing
– 3.5.8. Polymerase Chain Reaction Typing
– 3.5.9. Multilocus Sequence Typing
– 3.5.10. Variable Number Tandem Repeat Analysis
– 3.5.11. Whole Genome Based Typing
3.6. Recommended Reading
3.7. Websites

Chapter 4: Bacterial Growth, Physiology, and Death

4.1. Bacterial Growth
– 4.1.1. Types of Growth
– 4.1.2. Growth Phases in Broth Culture
– 4.1.3. Media for Bacterial Growth
– 4.1.4. Media Used for Isolation and Identification of Pathogens
– 4.1.5. Selective and Indicator Media
– 4.1.6. Media for Laboratory Studies
4.2. Bacterial Physiology
– 4.2.1. Nutritional Types
– 4.2.2. Physical Conditions Required for Growth
– 4.2.3. Growth Atmosphere
– 4.2.4. Growth Temperature
– 4.2.5. Extremophiles
– 4.2.6. Bacterial Metabolism
– 4.2.7. Adaptive Responses in Bacteria
– 4.2.8. Bacterial Defence Against Noxious Chemicals
4.3. Bacterial Viability and Death
4.4. Bacterial Death
4.5. Sterilization and Disinfection
– 4.5.1. Key Definitions
– Sterilization
– Disinfection
– Antisepsis
– 4.5.2. Methods Used in Sterilization and Disinfection
– Heat
– Ionizing Radiation
– Filtration
– Gaseous Chemical Agents
– Liquid Chemical Agents
– 4.5.3. Choice of Method
– 4.5.4. Measurement of Microbial Death (D Value)

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