Traumatic Brain and Spinal Cord Injury 1st edition by Cristina Morganti Kossmann, Ramesh Raghupathi, Andrew Maas ISBN 1107007437 978-1107007437

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Product details:

ISBN 10: 1107007437
ISBN 13: 978-1107007437
Author: Cristina Morganti Kossmann, Ramesh Raghupathi, Andrew Maas 

Traumatic Brain and Spinal Cord Injury comprehensively covers the medical and pathological issues related to neurotrauma and its often devastating consequences. Written by globally renowned experts in the field, both clinicians and researchers will find this book invaluable to update their knowledge. This volume is divided into two sections, one covering the brain, the other the spinal cord. Each section discusses the following topics: • The demographic in the developed and developing world where neurotrauma is witnessing a massive expansion • Major clinical issues including advanced semi-experimental monitoring techniques utilized by neurosurgeons and intensivists and the potential use of identifying markers of tissue injury • Overview of major pathophysiological changes • The development of animal models; successes and limitations • Past, current and future therapeutic strategies including rehabilitative opportunities. Presenting the most up-to-date clinical and experimental research in neurotrauma, this volume is essential reading for neurologists, neurosurgeons, intensive care physicians and rehabilitative physicians.

Traumatic Brain and Spinal Cord Injury 1st Table of contents:

Section 1 – Traumatic Brain Injury

1. Current evaluation of TBI epidemiology in an ageing society with improved preventive measures

2. Neurotrauma: an emerging epidemic in low- and middle-income countries

3. Blast-induced traumatic brain injury and post-traumatic stress disorder

4. Psychological effects of mild traumatic brain injury: their nature and treatment

5. Developments of neuroimaging techniques to diagnose and visualize white matter damage

6. New advances in monitoring the injured brain metabolism

7. Potential use and limitations of microdialysis for monitoring of neurochemical changes after TBI

8. Metabolic and therapeutic differences in pediatric and adult TBI: implications for clinical care and therapeutic hypothermia

9. Utility of biomarkers for diagnosis and prognosis of traumatic brain injury

10. Animal models of mild and severe TBI: what have we learned in the past 30 years?

11. Pediatric brain trauma: what do age-appropriate animal models teach us about the age-at-injury effect?

12. The complexity of traumatic axonal injury

13. Cerebral inflammation after traumatic injury: regulation of secondary damage, repair or both?

14. Controversial findings on the role of NMDA receptors in traumatic brain injury

15. Plasticity and recovery of the injured brain

16. Design and analysis of clinical trials in TBI

17. Future perspectives for the treatment of traumatic brain injury patients: decompressive craniectomy, hypothermia and erythropoietin

Section 2 – Traumatic Spinal Injury

18. Global epidemiology of traumatic spinal cord injury

19. Classification and surgical stabilization of the injured spine

20. Spinal cord injury: pathophysiology and prospect of decompressive surgical treatment

21. Modeling the injured spinal cord to match the human condition

22. Myelin inhibitors of neurite outgrowth in spinal cord injury

23. Controversies on the role of inflammation in the injured spinal cord

24. Cell transplantation for spinal cord injury

25. Combining transplant-based and pharmacological interventions with behavioral training and exercise for recovery from chronic spinal cord injury

26. Chances and limits of locomotor training after damage to the central nervous system

27. Temperature management and therapeutic hypothermia for the treatment of spinal cord injury

28. Spinal cord injury clinical trials

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