Biobanking in the 21st Century 1st edition by Feridoun Karimi Busheri – Ebook PDF Instant Download/Delivery: 3319205781, 978-3319205786
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ISBN 10: 3319205781
ISBN 13: 978-3319205786
Author: Feridoun Karimi Busheri
Biobanking, an emerging field supported by academia, industry and health administrators alike, is distinctly different today from the practice that once defined it. The science of Biobanking, which initially involved simply storing blood or tissue samples in a freezer, is now a highly sophisticated field of research, and expected to grow exponentially over the next decade or two. This book aims to serve the purpose of further enriching the available literature on Biobanking, by offering unique and more useful collection of ideas for the future. The book outlines the experiences of developing modern Biobanking repositories in different countries, whilst covering specific topics regarding the many aspects of Biobanking. This book will be of interest to a wide range of readers including: academics, students, volunteers and advocates of patients’ rights.
Biobanking in the 21st Century 1st Table of contents:
1: Integration, Networking, and Global Biobanking in the Age of New Biology
1.1 Introduction
1.2 Towards the Consensus on a Definition
1.3 The Age of New Biology
1.4 Integration and Networking
1.5 Revolutionary Milestones
1.5.1 Human Genome
1.5.2 Computers, Bioinformatics, and Common Language
1.5.3 Post-genomic Era
1.5.4 Advances in Technical Storage
1.6 Harmonization and Standardization Is the Key
1.7 Financial Prospects of Biobanking
1.8 Conclusion
References
2: The Future of Biobanking: A Conceptual Look at How Biobanks Can Respond to the Growing Human
2.1 Introduction
2.2 The Biobanking Industry Today
2.3 The Future of Biobanks
2.4 Increasing Biospecimen Supply
2.4.1 Commercial Biobanks
2.4.2 National and Regional Biobanks
2.4.3 Biobanking Networks
2.4.4 New Sources of Biospecimens
2.5 Biobanking Strategies of the Future
2.5.1 The Research Ready Hospital Concept
2.5.2 Adopting Sustainable Biobanking Practices
2.6 Conclusion
References
3: Sustainability of Biobanks in the Future
3.1 Introduction
3.2 Economics of a Biorepository
3.3 Academic Biorepositories
3.4 Other Economic Models
3.5 Conclusion
References
4: Biobanking: The Future of Cell Preservation Strategies
4.1 Introduction
4.2 Hypothermic Storage
4.3 Hypothermic Continuum
4.4 Cryopreservation Process
4.5 Vitrification Strategies
4.6 Sample Thawing
4.7 Post-storage Outcome
4.8 Cryopreservation Induced Cell Death
4.8.1 Physical Cell Rupture
4.8.2 Necrosis
4.8.3 Apoptosis
4.8.4 Necroptosis
4.8.5 Transitional Cell Death
4.9 Re-optimization of Cryopreservation
4.9.1 Initiation of Cryopreservation-Induced Molecular Death
4.9.2 Management of Cell Death
4.9.3 Carrier Media
4.9.4 Target Control of Apoptosis
4.10 Summary
References
5: Biobanking for Personalized Medicine
5.1 Introduction
5.2 Biospecimen Procurement and Processing
5.3 Biospecimens Storage and Distribution
5.4 Quality Assurance and Quality Control
5.5 Role of Pathologist in Biobanking
5.6 Whole Genome and Exome Sequencing
5.7 Managing Incidental Findings
5.8 Conclusions
References
6: A Global View of Breast Tissue Banking
6.1 Introduction
6.2 Breast Cancer Tissue Banks
6.3 Normal Breast Tissue
6.4 Challenges for Biobanks
6.5 The Economics of Biobanking
6.6 Summary
References
7: Biobanking of Cerebrospinal Fluid for Biomarker Analysis in Neurological Diseases
7.1 Introduction: Relevance of CSF Analysis
7.1.1 What Is CSF?
7.1.2 What Is Unique for CSF Biobanking?
7.2 Effect of Pre-analytical Factors on CSF Biomarkers During Biobanking
7.2.1 Pre-analytical Variation Due to Patient-Related Factors
7.2.2 Pre-analytical Variation Due to Laboratory Processing
7.2.3 Effects of Long-Term Storage of CSF
7.2.4 Quality Control in CSF Biobanking
7.3 Outlook
References
8: Biobanking in the Twenty-First Century: Driving Population Metrics into Biobanking Quality
8.1 Introduction
8.2 Population Metrics to Improve Biomarker Research
8.3 Implementing Population-�Based Biospecimen Collection
8.3.1 Advancing Biobanking in Alberta, Canada
8.4 Integrated Biobanking Models
8.5 Population Metrics in Biospecimen Distribution
8.6 Biobanking Networks
8.7 Key Consideration for Biospecimen Quality
8.7.1 Pre-intervention Biospecimens
8.8 Population-Based Tissue Collection
8.9 Sustainability of Population-Based Biospecimen Collection
8.10 Conclusions
References
9: Challenges in Developing a Cancer Oriented-Biobank: Experience from a 17 Year-Old Cancer Biob
9.1 Introduction
9.2 Background
9.3 Operational Issues
9.3.1 Standard Operating Procedures (SOPs)
9.3.2 Quality Control Issues
9.3.3 Long-Term Sustainability
9.4 Ethical Issues
9.5 Concluding Remarks
References
10: China Biobanking
10.1 Introduction
10.2 Chinese Biobanks
10.2.1 Disease-Oriented Biobanks
10.2.2 Population-Based Biobanks
10.2.3 Characteristic China Biobanks
10.3 The Status Quo of Chinese Biobanks
10.3.1 Biobank Scale
10.3.2 Specimen and Related Data Sharing
10.3.3 Biobank Staff
10.3.4 Laws and Regulations
10.3.5 Funding
10.4 Ethical Issues
10.5 International Cooperation
10.5.1 Scientific Research
10.5.2 Commercial Partnerships
10.5.3 Academic Exchanges
10.6 Prospects for Twenty-First Century Chinese Biobanks
10.6.1 Standardization of the Procedures
10.6.2 Sample Management
10.6.3 The Cooperation and Communication Among Biobanks
10.6.4 Developing Trends for Specimen Conservation
References
11: Establishing an Iso-Compliant Modern Cancer-Biobank in a Developing Country: A Model for In
11.1 Introduction
11.2 Perception for Biomedical Research and Biobanking in Jordan and the Middle East
11.2.1 The Experience of Establishing the First Cancer Biobank
11.2.2 Ethical, Legal and Social Issues (ELSI) Policy Development
11.2.3 Implementing Quality Measures by Developing a Quality Management System
11.2.4 Validating Sample Collection, Storage and Distribution
11.2.5 Biobank Safety and Security Measures
11.2.6 Qualification and Validation of Equipment and System’s Infrastructure
11.2.7 Personnel
11.2.8 Dissemination and Impact on Health and Society
11.2.9 Health Impact
11.2.10 Economic Impact
11.2.11 Utilization of KHCCBIO Bank by Middle East Countries
11.2.12 Collaborations at a Global Level
11.3 Conclusion
References
12: Nursing and Biobanking
12.1 Introduction
12.2 Nursing Roles Impacting Biobanking
12.3 Nurse Scientists
12.4 Research Nurse Coordinators
12.5 Clinical Research and Practice Nurses
12.6 Genetic and Genomic Nurse Competency Standards Impacting Biobanking Practices
12.7 Ethical Genetic and Genomic Considerations for Nursing Research and Practice Involving Biob
12.8 Conclusion
References
13: A Data-Centric Strategy for Modern Biobanking
13.1 Introduction
13.2 Sample-Centered Strategy and the Impact on Data
13.3 A Data-Centric Strategy for Biobanks
13.4 Conclusion
References
14: The Importance of Quality Patient Advocacy to Biobanks: A Lay Perspective from Independent C
14.1 Introduction
14.2 Different Models: Specific Examples
14.2.1 “Science for Education”: A Participant Experience
14.2.2 Breast Cancer Campaign Tissue Bank
14.2.3 Brain Tumour Tissue Bank: The Brainstrust Proposal
14.2.4 Confederation of Cancer Biobanks
14.2.5 Local Cancer Partnership Research Group Event: October 2013
14.2.6 A New and Innovative Patient-Led Consent Pathway for the Nottingham Health Science Biob
14.3 Lay Involvement in Action: What Is Possible?
14.4 Feedback of Findings to Donors of Tissue for Research
14.5 Validations from Researchers
14.6 Conclusions
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