Bicuspid Aortic Valve Diagnosis Surgical Treatment and Complications 1st edition by Anthony Chapman ISBN 1634827867 978-1634827867

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ISBN 10: 1634827867
ISBN 13: 978-1634827867
Author: Anthony Chapman 

Bicuspid aortic valve (BAV) is the most common congenital pathology of the aortic valve occurring in 0.5-2% of the general population and frequently requiring surgical management after the fourth decade of life. From the etiology to the surgical management of BAV is analyzed. Other chapters review genome-wide association studies, linkage analyses and next-generation sequencing studies, which are beginning to build a more comprehensive picture of the genetic bases of BAV. The prospects for developing tools for genetic screening of families and for risk stratification are explored as well, including the future steps which are necessary for the creation of an individualized approach to managing BAV. The last chapter is a review of the present understanding of ascending thoracic aortic aneurysm pathogenesis. The genetic basis and basic pathology underlying BAV and ascending thoracic aortic aneurysms are discussed as well, and are compared to known mechanisms underlying other aortopathologies. (Imprint: Nova Biomedical)

Bicuspid Aortic Valve Diagnosis Surgical Treatment and Complications 1st Table of contents:

1. Bicuspid Aortic Valve Syndrome: From the Etiology to the Surgical Strategies of Treatment
   (Paolo Nardi, Marco Russo, Antonio Pellegrino, and Luigi Chiariello, Policlinico Universitario Tor Vergata, Tor Vergata University of Rome, Rome, Italy)
2. Genetic Influences on Phenotype in Bicuspid Aortic Valve: Screening, Diagnosis and Prognosis
   (Catherine Francis and John Pepper, NIHR Cardiovascular BRU, Royal Brompton Hospital; National Heart & Lung Institute, Imperial College London and Institute of Cardiovascular Medicine and Science, London/Liverpool, England)
3. Genetic Basis, Pathogenesis and Histopathology of Aortopathy in Bicuspid Aortic Valve and Marfan Syndrome
   (Junfeng Yan^a, Ann-Cathrin Lehsau^a, Pamela Lazar-Karsten^a, Detlev Schult-Badusche^a, Luc Mertens^b, Bart L. Loeys^c, Salah A. Mohamed^a, ^aDepartment of Cardiac and Thoracic Vascular Surgery, UK SH-Campus Luebeck, Luebeck, Germany; ^bThe Hospital for Sick Children, Toronto, Candada; ^cCenter of Medical Genetics, University of Antwerp and University Hospital of Antwerp, Belgium, Radhoud University, Nijmegen, The Netherlands)
4. Index

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Tags: Anthony Chapman, Bicuspid Aortic, Surgical Treatment