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ISBN 10: 1107064775
ISBN 13: 978-1107064775
Author: Insoo Hyun

Despite years of heated social controversy over the use of human embryos in embryonic stem cell research, the caravan of stem cell science continues to proceed at an unrelenting pace all around the world. Bioethics and the Future of Stem Cell Research urges readers to look beyond the embryo debate to a much wider array of ethical issues in basic stem cell science and clinical translational research, including research involving adult and induced pluripotent stem cells. Insoo Hyun offers valuable insights into complex ethical issues ranging from pre-clinical animal studies to clinical trials and stem cell tourism, all presented through a unique blend of philosophy, literature and the history of science, as well as with Dr Hyun’s extensive practical experiences in international stem cell policy formation. This thoughtful book is an indispensable resource for anyone interested in the science of stem cells and the practical and philosophical elements of research ethics.
 

Bioethics and the Future of Stem Cell Research 1st Table of contents:

1. Prologue: The Dogs Bark but the Caravan Moves On

The Rise of Science and the Ethics of Modernity

Power and Uncertainty

Stem Cell Research: New Science and Old Tensions

What Is Bioethics?

The Chimera Myth and Two Major Themes

2. A Shifting Terrain: The Dynamics of Stem Cell Research

Stem Cells as a Scientific and Philosophical Object of Analysis

Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells vs. Human Embryonic Stem Cells

The Role of Stem Cells in Biomedical Research

Uncharted Territories

3. The Golden Bridle I: Philosophical Research Ethics

The Priority Question

More Conceptual Dynamics

Philosophical Research Ethics

Balancing and the Incommensurability Problem

4. The Golden Bridle II: Practical Research Ethics

From Belmont Principles to Federal Regulation

Toward Stem Cell–Specific Policies

New Directions, New Questions

5. Pegasus and the Chimera: Stem Cell–Based Animal Research

Chimeras – Past, Present, and Future

Chimera Research Oversight

6. The Limit Case: Acute Human/Nonhuman Neurological Chimerism

Setting Up the Limit Case

Searching for Factor X

Self-Consciousness

Some Preliminary Conclusions

What Else Might the Limit Case Teach Us?

7. Human Trials: Testing Stem Cell–Based Biologics in Patients

Different Perspectives, Different Interests

The Challenges Facing Stem Cell–Based Clinical Trials

Guidelines for Stem Cell–Based Clinical Trials

Issues in Trial Design

The Incommensurability Problem Revisited

8. Still the Sky Is Blue: Stem Cell Tourism and Medical Innovation

The Complexities of Stem Cell Tourism

Innovative Therapies Are Grounded in Patient Care

Innovative Therapies Can Help Advance the Stem Cell Field

Expanded Access and Off-Label Uses of Stem Cells

Chartering a Way Forward

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