Biopsy Interpretation of the Prostate 5th Edition by Jonathan Epstein, George Netto – Ebook PDF Instant Download/Delivery: 1451186746, 978-1451186741
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Product details:
ISBN 10: 1451186746
ISBN 13: 978-1451186741
Author: Jonathan Epstein, George Netto
Looking to master the prostate biopsy? Then it’s time to place Biopsy Interpretation of the Prostate prominently on your medical bookshelf. Under the guidance of top experts, you’ll learn the state-of-the-art, illustrated guide to prostate biopsy pathology interpretation. Authored by the field’s most established experts, you’ll learn to employ the best utilization of H&E microscopy along with the latest immunohistochemical markers in order to deliver accurate, reliable diagnoses.
With access to 350 full-color illustrations you’ll learn firsthand the intricacies and nuances of the full range of benign and malignant prostatic entities. The text will also prime you on how to critically use adjunctive tests to both diagnose limited prostate cancer and avoid overdiagnosing mimickers of prostate cancer.
In addition to improving your diagnostic skills, this book emphasizes the updated Gleason grading system so that you can provide the most accurate prognostication in your biopsy reports.
Feel more confident with challenging prostate biopsies; deliver the best in prostate cancer care by mastering biopsy pathology interpretation.
Biopsy Interpretation of the Prostate 5th Table of contents:
1 Clinical Correlates with Biopsy: Serum Prostate-Specific Antigen, Digital Rectal Examination, and Imaging Techniques
DIGITAL RECTAL EXAMINATION
IMAGING TECHNIQUES
PROSTATE-SPECIFIC ANTIGEN
Total Serum Prostate-Specific Antigen
Prostate-Specific Antigen Density
Age-Specific Prostate-Specific Antigen Reference Ranges
Prostate-Specific Antigen Velocity (Rate of Change of Prostate-Specific Antigen)
Molecular Forms of Prostate-Specific Antigen
Other Prostate Serum and Urine Markers
Prostate-Specific Antigen Factored into TNM Staging
Prostate-Specific Antigen Relation to Post-therapy Follow-up Biopsies
2 Needle Biopsy Technique, Tissue Sampling, and Processing of Needle Biopsy and Transurethral Resection Specimens
NEEDLE BIOPSY TECHNIQUE
NEEDLE BIOPSY PROCESSING—FIXATIVE
NEEDLE BIOPSY PROCESSING—NUMBER OF LEVELS
NEEDLE BIOPSY PROCESSING—INTERVENING UNSTAINED SLIDES
NEEDLE BIOPSY PROCESSING—NUMBER OF TISSUE CORES PER BLOCK/SLIDE
NEEDLE BIOPSY—INKING THE PERIPHERAL END OF THE CORE
SAMPLING OF TRANSURETHRAL RESECTION SPECIMENS
3 Gross Anatomy and Normal Histology
GROSS ANATOMY
HISTOLOGY
BENIGN PROSTATIC HYPERTROPHY
4 Inflammatory Conditions
ACUTE AND CHRONIC PROSTATIC INFLAMMATION
MALAKOPLAKIA
SARCOIDOSIS
GRANULOMATOUS PROSTATITIS
MYCOTIC PROSTATITIS
MYCOBACTERIAL PROSTATITIS
NONSPECIFIC GRANULOMATOUS PROSTATITIS
POSTBIOPSY GRANULOMAS
SYSTEMIC GRANULOMATOUS PROSTATITIS
MISCELLANEOUS INFECTIONS
5 Noninvasive Lesions in the Prostate: Prostatic Intraepithelial Neoplasia and Intraductal Carcinoma of the Prostate
PROSTATIC INTRAEPITHELIAL NEOPLASIA
Evidence Linking Prostatic Intraepithelial Neoplasia to Cancer
Mimickers of Prostatic Intraepithelial Neoplasia
Low-Grade Prostatic Intraepithelial Neoplasia: Risk of Cancer on Rebiopsy
High-Grade Prostatic Intraepithelial Neoplasia: Incidence on Biopsy
High-Grade Prostatic Intraepithelial Neoplasia on Biopsy: Overall Risk of Cancer
High-Grade Prostatic Intraepithelial Neoplasia on Biopsy: Risk of Cancer Stratified by Clinical Predictors
High-Grade Prostatic Intraepithelial Neoplasia on Biopsy: Risk of Cancer Stratified by Pathologic Predictors
High-Grade Prostatic Intraepithelial Neoplasia on Biopsy: Repeat Biopsy Strategy and Technique
High-Grade Prostatic Intraepithelial Neoplasia: Significance on Transurethral Resection of the Prostate Material
High-Grade Prostatic Intraepithelial Neoplasia on Biopsy: Findings at Subsequent Radical Prostatectomy
INTRADUCTAL CARCINOMA OF THE PROSTATE
Incidence of Intraductal Carcinoma of the Prostate
Differential Diagnosis of Intraductal Carcinoma of the Prostate
Significance of Intraductal Carcinoma of the Prostate on Biopsy
6 Diagnosis of Limited Adenocarcinoma of the Prostate
DIAGNOSIS ON NEEDLE BIOPSY
General Principles in Diagnosing Prostate Cancer
ARCHITECTURAL FEATURES IN THE DIAGNOSIS OF CANCER
NUCLEAR FEATURES IN THE DIAGNOSIS OF CANCER
CYTOPLASMIC FEATURES IN THE DIAGNOSIS OF CANCER
INTRALUMINAL CONTENTS IN THE DIAGNOSIS OF CANCER
STROMAL CHANGES
HISTOLOGIC FEATURES SPECIFIC FOR PROSTATE CANCER
IDENTIFICATION OF BASAL CELLS ON H&E-STAINED SECTIONS
DIAGNOSIS OF LIMITED HIGH-GRADE CARCINOMA
CARCINOMAS MIMICKING BENIGN GLANDS
DIAGNOSIS OF CANCER ON TRANSURETHRAL RESECTION
USE OF IMMUNOHISTOCHEMICAL ADJUNCTIVE TESTS FOR DIAGNOSIS OF CARCINOMA
7 Mimickers of Prostate Adenocarcinoma
MIMICKERS OF GLEASON PATTERN 3 ADENOCARCINOMA
Adenosis
Diffuse Adenosis of the Peripheral Zone
Atrophy
Basal Cell Hyperplasia
Colonic Mucosa
Cowper Glands
Mesonephric Hyperplasia
Nephrogenic Adenoma
Radiation Atypia
Seminal Vesicles
Verumontanum Mucosal Gland Hyperplasia
MIMICKERS OF GLEASON PATTERNS 4 AND 5 ADENOCARCINOMA
Clear Cell Cribriform Hyperplasia
Nonspecific Granulomatous Prostatitis
Paraganglia
Sclerosing Adenosis
Signet Ring Lymphocytes
Xanthoma
8 Reporting Cancer: Influence on Prognosis and Treatment
NEEDLE BIOPSY
Use of Macros (Canned Text)
Quantification of Amount of Cancer on Needle Biopsy
LOCATION OF POSITIVE BIOPSY CORES
PERINEURAL INVASION
LYMPHOVASCULAR INVASION
USE OF NOMOGRAMS
DIRECT STAGING ON NEEDLE BIOPSY
TRANSURETHRAL RESECTION
Subclassification
9 Grading of Prostatic Adenocarcinomas
HISTORICAL BACKGROUND
INTERNATIONAL SOCIETY OF UROLOGICAL PATHOLOGY MODIFICATIONS TO GLEASON GRADING
2005 International Society of Urological Pathology Consensus Conference
2014 International Society of Urological Pathology Consensus Conference
GENERAL APPLICATIONS OF THE GLEASON GRADING SYSTEM
GLEASON PATTERNS
Historical Gleason Patterns 1 and 2
Gleason Pattern 3
Gleason Pattern 4
Gleason Pattern 5
GRADING VARIANTS OF PROSTATE CARCINOMA
Adenocarcinoma with Vacuoles
Foamy Gland Carcinoma
Pseudohyperplastic Adenocarcinoma
REPORTING GLEASON GRADE ON BIOPSY
Different Cores with Different Grades
Tertiary Gleason Patterns
Reporting Secondary Patterns of Higher Grade When Present to a Limited Extent
Reporting Secondary Patterns of Lower Grade When Present to a Limited Extent
Reporting Percentage Pattern 4 on Needle Biopsies
CORRELATION NEEDLE BIOPSY AND RADICAL PROSTATECTOMY GRADE
Explanations for Grading Discrepancies
Factors Associated with Increased Upgrading and Downgrading from Biopsy to Prostatectomy
INTEROBSERVER REPRODUCIBILITY
GLEASON GRADE GROUPING
CHANGE OF GRADE OVER TIME
USE OF ARTIFICIAL INTELLIGENCE FOR GRADING
10 Findings of Atypical Glands Suspicious for Cancer
INCIDENCE OF ATYPICAL DIAGNOSIS ON NEEDLE BIOPSY
INTEROBSERVER REPRODUCIBILITY
PROSTATE CANCER RISK FOLLOWING A DIAGNOSIS OF ATYPIA
RADICAL PROSTATECTOMY AFTER CANCER DIAGNOSED POSTATYPICAL BIOPSY
REBIOPSY TECHNIQUES FOLLOWING A DIAGNOSIS OF ATYPIA
HISTOLOGY–ATYPICAL SMALL GLANDS
11 Prostatic Duct Adenocarcinoma
12 Neuroendocrine Differentiation in the Benign and Malignant Prostate
NEUROENDOCRINE CELLS IN NORMAL PROSTATE HISTOLOGY
NEUROENDOCRINE CELLS AND DIFFERENTIATION IN PROSTATE CANCER
USUAL PROSTATE ADENOCARCINOMA WITH NEUROENDOCRINE DIFFERENTIATION
ADENOCARCINOMA WITH PANETH CELL-LIKE NEUROENDOCRINE DIFFERENTIATION
CARCINOID TUMOR
SMALL CELL CARCINOMA
LARGE CELL NEUROENDOCRINE CARCINOMA
MIXED NEUROENDOCRINE CARCINOMA–ACINAR ADENOCARCINOMA
PROSTATE CARCINOMA WITH OVERLAPPING FEATURES OF SMALL CELL AND ACINAR ADENOCARCINOMA
CASTRATE-RESISTANT PROSTATE CANCER WITH SMALL CELL CARCINOMA–LIKE CLINICAL PRESENTATION
13 Mucinous Differentiation in the Benign and Malignant Prostate
MUCINOUS ADENOCARCINOMA OF THE PROSTATE
PROSTATIC URETHRAL ADENOCARCINOMA
14 Benign and Malignant Prostate following Treatment
ANTIANDROGEN THERAPY
RADIATION
POSTRADICAL PROSTATECTOMY BIOPSIES
EMERGING FOCAL/ABLATIVE THERAPIES
Cryotherapy
High-Intensity Frequency Ultrasound
Vascular-Targeted Photodynamic Therapy
HYPERTHERMIA
PHYTOTHERAPY
POST-TEFLON INJECTION GRANULOMAS
POSTNEEDLE BIOPSY CHANGES
15 Urothelial Carcinoma
DISTINCTION OF HIGH-GRADE PROSTATIC ADENOCARCINOMA FROM UROTHELIAL CARCINOMA
PROSTATIC INTRADUCTAL UROTHELIAL CARCINOMA WITH OR WITHOUT PROSTATIC STROMAL INVASION
UROTHELIAL CARCINOMA SEEN ON NEEDLE BIOPSY
PRIMARY UROTHELIAL CARCINOMA
16 Mesenchymal Tumors and Tumor-like Conditions
STROMAL TUMORS OF UNCERTAIN MALIGNANT POTENTIAL AND STROMAL SARCOMAS
LEIOMYOMA/LEIOMYOSARCOMA
INFLAMMATORY MYOFIBROBLASTIC TUMOR
SOLITARY FIBROUS TUMOR
GASTROINTESTINAL STROMAL TUMOR
RHABDOMYOSARCOMA
MISCELLANEOUS
17 Miscellaneous Benign and Malignant Lesions
BENIGN LESIONS
Prostatic Cysts
Multilocular Cysts of the Prostate (Multilocular Prostatic Cystadenoma)
Melanotic Lesions
Amyloid
Calculi and Calcification
Infarcts
Miscellaneous
MALIGNANT LESIONS
Basal Cell Carcinomas
Carcinomas with Squamous Differentiation
Sarcomatoid Carcinoma
Hematopoietic Tumors
Miscellaneous Primary Tumors
Involvement of the Prostate by Secondary Tumors
18 Prostatic Urethral Lesions
PROSTATIC URETHRAL POLYPS
MISCELLANEOUS URETHRAL POLYPS
NEPHROGENIC ADENOMAS
INVERTED PAPILLOMA OF THE PROSTATIC URETHRA
MISCELLANEOUS
19 Tissue-based Biomarkers Using Needle Biopsy Material
COMMERCIAL GENOMIC ASSAYS
PTEN LOSS
Germ Line Testing for DNA Damage Repair Genes
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