Cardiac Mechano electric Coupling And Arrhythmias 2nd Edition by Peter Kohl, Frederick Sachs, Michael Franz – Ebook PDF Instant Download/Delivery: 0191636233, 9780191636233
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ISBN 10: 0191636233
ISBN 13: 9780191636233
Author: Peter Kohl, Frederick Sachs, Michael Franz
Cardiac Mechano-Electric Coupling and Arrhythmias offers a thoroughly reviewed compendium written by leading experts in the field on the mechanism and consequences of cardiac mechano-electrical coupling. Its coverage ranges from stretch-activated ion channels to mechanically induced arrhythmias and mechanical interventions for heart rhythm correction. Information is grouped into logical sections, from molecular mechanisms, to cell, tissue and whole organ responses, right through to patient-based observations and insight emerging from clinical trials. The information provided carefully highlights both consensus insight and current shortcomings in our understanding of cardiac mechano-electric coupling. The book has been thoroughly revised and expanded since publication of the first edition in 2005, extensively updated to reflect recent developments in the field, and now offers a more balanced view of mechano-electrical interactions in the heart and develops a more clinical focus. Written with the practising cardiologist and junior doctor in mind, it offers interesting new insight for the established physician with an interest in cardiac arrhythmogenesis and heart rhythm management.
Cardiac Mechano electric Coupling And Arrhythmias 2nd Table of contents:
1. Evolutionary origins of stretch-activated ion channels
Boris Martinac and Anna Kloda
2. Stretch-activated channels in the heart
Frederick Sachs
3. The mechano-gated K2P channel TREK-1 in the cardiovascular system
Eric Honoré and Amanda Patel
4. Cellvolume-sensitive ion channels and transporters in cardiac myocytes
Clive M. Baumgarten, Wu Deng and Frank J. Raucci, Jr
5. Non-sarcolemmal stretch-activated channels
Gentaro Iribe and Peter Kohl
6. Pacemaker, potassium, calcium, sodium: stretch modulation of the voltage-gated channels
Catherine E. Morris
7. Role ofcaveolae in stretch-sensing: implications for mechano-electric coupling
Sarah Calaghan
8. The membrane/cytoskeleton interface and stretch-activated channels
Thomas M. Suchyna and Frederick Sachs
9. Cardiomyocyte stretch-sensing
Michiel Helmes and Henk Granzier
10. Theresponseofcardiacmuscle to stretch: calcium and force
John Jeremy Rice and Donald M. Bers
11. Stretch effects on second messengers
Jean-Luc Balligand and Chantal Dessy
12. Functional implications of myocyte architecture
Kevin Kit Parker
Basic Science, Section II
13. Mechanical modulation of pacemaker electrophysiology
Patricia J. Cooper and Ursula Ravens
14. Mechano-electric coupling in working cardiomyocytes: diastolic and systolic effects
Michael R. Franz
15. Mechano-sensitivity of pulmonary vein cells: implications for atrial arrhythmogenesis
Chang Ahn Seol, Won Tae Kim, Jae Boum Youm, Yung E. Earm and Chae Hun Leem
16. Heterogeneity ofsarcomere length and function as a cause of arrhythmogenic calcium waves
Henk E.D.J.
17. Cellular mechanisms of arrhythmogenic cardiac alternans
Kenneth R. Laurita
18. Remodelling ofgapjunctions inventricular myocardium, effects of cell-to-cell adhesion, mediators of hypertrophy and mechanical forces
André G. Kléber and Jeffrey E. Saffitz
19. The origin of fibroblasts, extracellular matrix and potential contributions to cardiac mechano-electric coupling
Troy A. Baudino and Thomas K. Borg
20. Advantages and pitfalls ofcell cultures as model systems to study cardiac mechano-electric coupling
Leslie Tung and Susan A. Thompson
Basic Science, Section III
21. Activation sequence ofcardiac muscle in simplified experimental models: relevance for cardiac mechano-electric coupling
Vladimir S. Markhasin, Alexander Balakin, Yuri Protsenko and Olga Solovyova
22. Mechanical triggers and facilitators of ventricular tachy-arrhythmias
T. Alexander Quinn and Peter Kohl
23. Acute stretch effects on atrial electrophysiology
Michael R. Franz and Frank Bode
24. Stretch effects on potassium accumulation and alternans in pathological myocardium
Christian Bollensdorff and Max J. Lab
25. The effects ofwall stretch on ventricular conduction and refractoriness in the whole heart
Robert W. Mills, Adam T. Wright, Sanjiv M. Narayan and Andrew D. McCulloch
26. Mechanical triggers of long-term ventricular electrical remodelling
Darwin Jeyaraj and David S. Rosenbaum
27. Mechanisms of mechanical pre- and postconditioning
Asger Granfeldt, Rong Jiang, Weiwei Shi and Jakob Vinten-Johansen
Translational Science, Section IV
28. Mechano-electric coupling in chronic atrial fibrillation
Ulrich Schotten
29. Mechanically induced pulmonary vein ectopy: insight from animal models
Omer Berenfeld
30. Regional variation in mechano-electric coupling: the right ventricle
Ed White, David Benoist and Olivier Bernus
31. Mechanical induction of arrhythmia in the ex situ heart: insight into Commotio cordis
Frank Bode and Michael R. Franz
32. Arrhythmias in murine models of the mechanically impaired heart
Larissa Fabritz and Paulus Kirchhof
33. Studying cardiac mechano-sensitivity in man
Flavia Ravelli and Michela Masé
34. Mathematical models of cardiac structure and function: mechanistic insights from models of heart failure
Vicky Y. Wang, Martyn P. Nash, Ian J. LeGrice, Alistair A. Young, Bruce H. Smaill and Peter J. Hunter
35. Mathematical models of human atrial mechano-electrical coupling and arrhythmias
Elizabeth M. Cherry
36. Mathematical models of ventricular mechano-electric coupling and arrhythmia
Natalia A. Trayanova, Viatcheslav Gurev, Jason Constantino and Yuxuan Hu
Clinical Relevance, Section V
37. Load dependence of ventricular repolarization
Peter Taggart and Peter Sutton
38. Is the U wave in the electrocardiogram a mechano-electrical phenomenon?
Rainer Schimpf and Martin Borggrefe
39. Mechanical modulation of cardiac function: role of the pericardium
John V. Tyberg
40. Mechanically induced electrical remodelling in human atrium
Geoffrey Lee, Prashanthan Sanders, Joseph B. Morton and Jonathan M. Kalman
41. Drug effects and atrial fibrillation: potential and limitations
Jurren M. van Opstal, Yuri Blaauw and Harry J. G.M. Crijns
42. Stretch as a mechanism linking short-and long-term electrical remodelling in the ventricles
Eugene A. Sosunov, Evgeny P. Anyukhovsky and Michael R. Rosen
43. Volume and pressure overload and ventricular arrhythmogenesis
Michiel J. Janse and Ruben Coronel
44. Stretch effects on fibrillation dynamics
Masatoshi Yamazaki and Jerome Kalifa
Clinical Relevance, Section VI
45. Commotio Cordis: sudden death from blows to the chest wall
Mark S. Link
46. Repolarization changes in the synchronously and dyssynchronously contracting failing heart
Takeshi Aiba and Gordon F. Tomaselli
47. Ventricular arrhythmias in heart failure: link to haemodynamic load
Steven N. Singh and Pamela Karasik
48. Mechanical heterogeneity and after contractions as trigger for Torsades de Pointes
Annerie M.E. Moers and Paul G.A. Volders
49. Stretch-induced arrhythmias in ischaemia
Ruben Coronel, Natalia A. Trayanova, Xiao Jie and Michael J. Janse
Clinical Relevance, Section VII
50. Anti- arrhythmic effects of acute mechanical stimulation
Tommaso Pellis and Peter Kohl
51. Termination of arrhythmias by haemodynamic unloading
Peter Taggart and Peter Sutton
52. Mechanical modulation of defibrillation and resuscitation efficacy
Derek J. Dosdall, Harish Doppalapudi and Raymond E. Ideker
53. Anti- and proarrhythmic effects of cardiac assist device implantation
Paul J. Joudrey, Roger J. Hajjar and Fadi G. Akar
54. Anti- and proarrhythmic effects of cardiac resynchronisation therapy
Nico H.L. Kuijpers and Frits W. Prinzen
Clinical Relevance, Section VIII
55. Evidence for mechano-electric coupling from clinical trials on AF
Matthias Hammwóhner and Andreas Goette
56. Evidence for mechano-electric coupling from clinical trials on heart failure
Paulus Kirchhof and Günter Breithardt
57. Mechano-electric coupling and the pathogenesis of arryhthmogenic right ventricular cardiomyopathy
Hayden Huang, Angeliki Asimaki, Frank Marcus and Jeffrey E. Saffitz
58. Evidence for mechano-electric coupling from clinical trials on cardiac resynchronisation therapy
Nico R.L. Van de Veire and Jeroen J. Bax
59. Mechano-electric coupling in patients treated with ventricular assist devices: insights from individual cases and clinical trials
Cesare M. Terracciano, Michael Ibrahim, Manoraj Navaratnarajah and Magdi H. Yacoub
Outlook, Section IX
60. Measuring strain of structural proteins in vivo in real time
Fanjie Meng and Frederick Sachs
61. Roles of cardiac SAC beyond mechano-electric coupling: stretch-enhanced force generation and muscular dystrophy
David G. Allen and Marie L. Ward
62. Distributions of myocyte stress, strain and work in normal and infarcted ventricles
Elliot J. Howard and Jeffrey H. Omens
63. Evolving concepts in measuring ventricular strain in canine and human hearts: non-invasive imaging
Elisa E. Konofagou and Jean Provost
64. Evolving concepts in measuring ventricular strain in the human heart: impedance measurements
Douglas A. Hettrick
65. Mechano-sensitive channel blockers: a new class of antiarrhythmic drugs?
Ed White
Index
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Tags: Peter Kohl, Frederick Sachs, Michael Franz, Cardiac Mechano, electric Coupling


