Clinical Chemistry 8th Edition by William Marshall, Márta Lapsley, Andrew Day – Ebook PDF Instant Download/Delivery: 0723438846 , 9780723438847
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Product details:
ISBN 10: 0723438846
ISBN 13: 9780723438847
Author: William Marshall, Márta Lapsley, Andrew Day
Clinical Chemistry considers what happens to the body’s chemistry when affected by disease. Each chapter covers the relevant basic science and effectively applies this to clinical practice. It includes discussion on diagnostic techniques and patient management and makes regular use of case histories to emphasise clinical relevance, summarise chapter key points and to provide a useful starting point for examination revision.
The clear and engaging writing style appreciated by generations of readers has been retained in this new (eighth) edition, while the content has been thoroughly updated throughout. The approach and scope of this trusted text makes it ideal for integrated medical curricula for medical training and for students and practitioners of clinical and biomedical science. The complementary online version of the book, including additional self-assessment material, completes this superb learning package.
- Comes with complete, downloadable eBook on Student Consult
- Additional self-assessment materials – interactive clinical cases and two tier level MCQs (‘standard’ and ‘advanced’)
- New introductory chapter on basic biochemistry – including solutions, solutes, ionisation, pH, buffers, amino acids, peptides and proteins, enzyme activity, including kinetic properties, DNA structure
- ‘Light bulb’ sections give practical advice and clarify difficult concepts or potential pitfalls
- Updated references to core guidelines (UK and international) reflect latest best practice
Clinical Chemistry 8th Table of contents:
Chapter 1 An Introduction to Biochemistry and Cell Biology
Units and Measurements
Analytical Techniques
Ions and Molecules of Biological Importance
Elements of Cell Biology
Transport Mechanisms
Chapter 2 Biochemical Investigations in Clinical Medicine
Introduction
Use of Biochemical Investigations
Specimen Collection
Sample Analysis and Reporting of Results
Sources of Error
Interpretation of Results
The Clinical Utility of Laboratory Investigations
Clinical Audit
Screening
Chapter 3 Water, Sodium and Potassium
Introduction
Water and Sodium Homoeostasis
Water and Sodium Depletion
Water and Sodium Excess
Laboratory Assessment of Water and Sodium Status
Hyponatraemia
Hypernatraemia
Potassium Homoeostasis
Potassium Depletion and Hypokalaemia
Potassium Excess and Hyperkalaemia
Chapter 4 Hydrogen Ion Homoeostasis and Blood Gases
Introduction
Clinical and Laboratory Assessment of Hydrogen Ion Status
Disorders of Hydrogen Ion Homoeostasis
Interpretation of Acid–Base Data
Oxygen Transport and Its Disorders
Respiratory Failure and Respiratory Support
Chapter 5 The Kidneys
Introduction
The Biochemical Investigation of Kidney Function
Imaging and Renal Biopsy
Renal Disorders
Chapter 6 The Liver
Introduction
Bilirubin Metabolism
Biochemical Assessment of Liver Function
Liver Disease
Chapter 7 The Gastrointestinal Tract
Introduction
The Stomach
The Pancreas
The Small Intestine
Gastrointestinal Hormones
Chapter 8 Clinical Nutrition
Introduction
Vitamin Deficiencies
Water-Soluble Vitamins
Fat-Soluble Vitamins
Vitamins as Drugs
Trace Elements
Provision of Nutritional Support
Eating Disorders
Obesity
Chapter 9 The Hypothalamus and the Pituitary Gland
Introduction
Anterior Pituitary Hormones
Measurement of Anterior Pituitary Hormones
Disorders of Anterior Pituitary Function
Posterior Pituitary Hormones
Chapter 10 The Adrenal Glands
Introduction
Adrenal Steroid Hormone Biosynthesis
Measurement of Adrenal Steroid Hormones
Disorders of the Adrenal Cortex
Disorders of the Adrenal Medulla
Chapter 11 The Thyroid Gland
Introduction
Thyroid Hormones
Tests of Thyroid Function
Disorders of the Thyroid
Chapter 12 The Gonads
Introduction
Disorders of Male Gonadal Function
Disorders of Female Gonadal Function
Pregnancy
Chapter 13 Disorders of Carbohydrate Metabolism
Introduction
Measurement of Glucose Concentration
Diabetes Mellitus
Metabolic Complications of Diabetes
Diabetes in Pregnancy
Glycosuria
Glucose in Cerebrospinal Fluid
Hypoglycaemia
Hypoglycaemia in Childhood
Chapter 14 Calcium, Phosphate and Magnesium
Introduction
Bone
Plasma Calcium
Calcium-Regulating Hormones
Calcium and Phosphate Homoeostasis
Disorders of Calcium, Phosphate and Magnesium Metabolism
Chapter 15 Bones and Joints
Introduction
Metabolic Bone Diseases
Articular Disease
Chapter 16 Plasma Proteins and Enzymes
Introduction
Measurement of Plasma Proteins
Specific Plasma Proteins
Immunoglobulins
Cytokines
Plasma Enzymes
Chapter 17 Lipids, Lipoproteins and Cardiovascular Disease
Introduction
Triglycerides, Cholesterol and Phospholipids
Classification of Lipoproteins
Lipoprotein Metabolism
Lipid Investigations
Disorders of Lipid Metabolism
Cardiovascular Risk Management
Lipoprotein Deficiency
Myocardial Infarction
Heart Failure
Hypertension
Chapter 18 Muscles, Nerves and Psychiatric Disorders
Introduction
Muscle Diseases
Nervous System Disease
Psychiatric Disease
Chapter 19 Inherited Metabolic Diseases
Introduction
Inherited Metabolic Disorders
Diagnosis
Newborn Screening
Prenatal Diagnosis
DNA Analysis
Treatment
Chapter 20 Disorders of Haemoproteins, Porphyrins and Iron
Introduction
Haemoproteins
Porphyrins
Iron
Chapter 21 Metabolic Aspects of Malignant Disease
Introduction
Paraneoplastic Endocrine Syndromes
Other Metabolic Complications of Malignant Disease
Cancer Cachexia
Carcinoid Tumours
Multiple Endocrine Neoplasia
Tumour Markers
Conclusion
Chapter 22 Therapeutic Drug Monitoring and Chemical Aspects of Toxicology
Introduction
Therapeutic Drug Monitoring
Monitoring of Specific Drugs
Toxicology
Poisoning with Specific Agents
Screening for Drugs
Pharmacogenomics
Chapter 23 Clinical Chemistry at the Extremes of Age
Old Age
Childhood
Appendix Adult Reference Ranges
Index
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Tags: William Marshall, Márta Lapsley, Andrew Day, Clinical Chemistry