Clinical Magneto encephalography and Magnetic Source Imaging 1st edition by Andrew Papanicolaou – Ebook PDF Instant Download/Delivery: 0521873754, 9780521873758
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ISBN 10: 0521873754
ISBN 13: 9780521873758
Author: Andrew Papanicolaou
This is the first volume to explore the field of clinical magnetoencephalography (MEG) and magnetic source imaging (MSI), the techniques measuring the magnetic fields generated by neuronal activity in the brain. Describing the empirical knowledge gained during the last two decades, this book will serve as a basis for the training of clinicians and scientists entering this new and exciting field. The book covers the methods for recording MEG and performing MSI in a clinical setting and includes practical examples of data collection and analysis. It explains why MEG should be used in the evaluation and treatment of patients being considered for epilepsy surgery, concluding with a section describing the potential for future applications of these methods. This is essential reading for graduate students in clinical neuroscience, residents in neurology and psychiatry, neuroradiology and neurosurgery, specialists in neurophysiology and epilepsy, and clinicians in a wide range of related brain sciences.
Clinical Magneto encephalography and Magnetic Source Imaging 1st Table of contents:
Section 1: The Method
- Basic Concepts
- The Nature and Origin of Magnetic Signals
- Recording the Magnetic Flux
- Overview of MSI Using the Single Equivalent Current Dipole (ECD) Model as an Example
- The Fundamental Problems of MSI
- Head Models
- Spherical Models
- Boundary Element Models
- Finite Element/Finite Difference Models
- Source Models – Discrete Source Models
- Discrete Source Models
- The Single ECD Model
- Multiple ECD Models
- Reliability of the Estimated Sources
- Source Models – Distributed Source Models
- Distributed Source Models
- Minimum-Norm Models
- Regularization Methods
- Source Models – Beamformers
- Pragmatic Features of the Clinical Use of MEG/MSI
- References
Section 2: Spontaneous Brain Activity
- MEG Recordings of Spontaneous Brain Activity – General Considerations
- Head Positioning
- Recording Time
- Sampling Rate
- Simultaneous MEG/EEG Recordings
- Recordings During the Resting State
- Recordings During Sleep
- Elicitation of Abnormal Activity via Hyperventilation
- Elicitation of Abnormal Activity via Drugs
- The Use of Sedation
- Normal Spontaneous MEG – Frequently Encountered Artifacts
- Muscle (EMG) Activity
- Eye Blinks
- Cardiac Artifacts
- Respiratory Artifacts
- Artifacts from Ferromagnetic Dental Implants
- Artifacts from Magnetized EEG Electrodes
- Environmental Artifacts
- Spontaneous MEG Morphology
- Morphology of Normal MEG Waveforms
- Vertex Waves
- K-Complex
- Lambda Waves and Positive Occipital Sharp Transients of Sleep (POSTS)
- Sleep Spindles
- Mu Waves
- Benign Epileptic Transients of Sleep (BETS)
- Hypnagogic Hypersynchrony
- Frequency Bands of Normal Spontaneous MEG
- Alpha Waves
- Beta Waves
- Theta Waves
- Delta Waves
- Abnormal Spontaneous MEG
- Abnormal Slow Waves
- Spikes, Sharp Waves, and Polyspikes
- Abnormal Wave Patterns
- Definition of MEG Spikes and Patterns
- MEG and Epilepsy
- Ictal Discharges
- Contributions of MEG to the Surgical Management of Epilepsy – General Considerations
- Definitions
- Ictal MEG Investigations
- Comparison of Interictal MEG with Interictal and Ictal EEG
- Surgical Outcome
- Provocation Methods
- Source Localization Techniques in Adult Epilepsy
- Alternative Localization Methods
- MEG Investigations in Lesional Epilepsies
- Brain Tumors
- Vascular Malformations
- Cortical Malformations
- MEG Investigations in Nonlesional Epilepsies
- Nonlesional Temporal Lobe Epilepsies (TLEs)
- Extratemporal Lobe Epilepsies (ETLEs)
- Pediatric Nonlesional Epilepsy Surgery
- Overview
- Lobectomy or Topectomy Candidates
- Corpus Callosotomy
- Nonlesional Refractory Status Epilepticus
- Conclusion
- References
Section 3: Evoked Magnetic Fields
- Recording Evoked Magnetic Fields (EMFs)
- Overview
- General Instructions for Recording EMFs
- Replications
- Data Storage
- Artifact Removal
- Removing “Bad” Channels
- Filtering and Electromagnetic-Noise Reduction
- Averaging
- Somatosensory Evoked Fields (SEFs)
- Overview of SEFs
- Recording SEFs
- Stimulation
- Recording Parameters
- Normative SEF Data
- Aberrant SEFs
- Referral Questions That May Be Addressed with SEFs
- Movement-Related Magnetic Fields (MRFs) – Motor Evoked Fields (MEFs)
- Overview of MRFs
- Recording MRFs
- Elicitation
- Triggering
- Recording Parameters
- Eye- and Body-Movement Artifacts
- Normative MRF Data
- Referral Questions That May Be Addressed with MRFs
- Auditory Evoked Magnetic Fields (AEFs)
- Overview of AEFs
- Recording AEFs
- AEF Sources
- Stimulation
- Recording Parameters
- Normative AEF Data
- Aberrant AEFs
- Referral Questions That May Be Addressed with AEFs
- Visual Evoked Magnetic Fields (VEFs)
- Overview of VEFs
- Recording VEFs
- VEF Sources
- Stimulation
- Recording Parameters
- Normative VEF Data
- Aberrant VEFs
- Referral Questions That May Be Addressed with VEFs
- Language-Related Brain Magnetic Fields (LRFs)
- Overview of LRFs
- Recording LRFs
- LRF Sources
- Stimulation
- Patient Alertness and Cooperation
- Recording Parameters
- Data Processing
- Normative LRF Data
- Hemispheric Dominance for Language
- Functional Mapping of the Receptive and Expressive Language-Specific Cortex
- Aberrant LRFs
- Alternative Techniques for Evoked Magnetic Field Data – Future Directions
- Spectral Analysis of MEG Data
- Event-Related Desynchronization (ERD) and Event-Related Synchronization (ERS)
- Temporal Spectral Evolution (TSE)
- Coherence
- Direct Transfer Function (DTF)
- References
Postscript: Future Applications of Clinical MEG
- Overview
- Normal Aging and Neurodegenerative Disorders
- Age-Dependent Changes in Cognition
- Alzheimer’s Disease and Mild Cognitive Impairment
- Parkinson’s Disease and Lewy Body Dementia
- Neurodevelopmental Disorders
- Fetal MEG
- Dyslexia
- Autism Spectrum Disorders
- Attention Deficit Hyperactivity Disorder (ADHD)
- Epileptic Aphasia
- Psychiatric Disorders
- Schizophrenia
- Depression
- Obsessive-Compulsive Disorder (OCD)
- Post-Traumatic Stress Disorder (PTSD)
- Neurological Disorders
- Tinnitus
- Tremor Syndromes
- Multiple Sclerosis (MS)
- Brain Tumors
- Cerebral Ischemia and Stroke
- Functional Reorganization
- Cerebrovascular Disease
- References
- Index
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Andrew Papanicolaou,Clinical Magneto,Magnetic Source