Essentials of Stem Cell Biology 3rd Edition by Robert Lanza, Anthony Atala ISBN 0124104274 9780124104273

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Product details:

ISBN 10: 0124104274
ISBN 13: 978-0124104273
Author: Robert Lanza, Anthony Atala
Essentials of Stem Cell Biology 3rd Edition: First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners, and students embracing the latest advances in stem cells. Representing the combined effort of 7 editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world’s experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, and methods to the application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered.

• Contributions by Nobel Laureates and leading international investigators
• Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough
• Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate
• Presented in full color with a glossary, highlighted terms, and bibliographic entries replacing references

 

Essentials of Stem Cell Biology 3rd Table of contents:

I: Introduction to Stem Cells

1. Why Stem Cell Research? Advances in the Field
2. ‘Stemness’: Definitions, Criteria, and Standards
3. Pluripotent Stem Cells from Vertebrate Embryos: Present Perspective and Future Challenges
4. Embryonic Stem Cells in Perspective
5. The Development of Epithelial Stem Cell Concepts

II: Basic Biology and Mechanisms

6. Stem Cell Niches
7. Mechanisms of Stem Cell Self-Renewal
8. Cell Cycle Regulators in Stem Cells
9. How Cells Change Their Phenotype

III: Tissue and Organ Development

10. Differentiation in Early Development
11. Stem Cells Derived from Amniotic Fluid
12. Stem and Progenitor Cells Isolated from Cord Blood
13. The Nervous System
14. Sensory Epithelium of the Eye and Ear
15. Epithelial Skin Stem Cells
16. Hematopoietic Stem Cells
17. Peripheral Blood Stem Cells
18. Multipotent Adult Progenitor Cells
19. Mesenchymal Stem Cells
20. Skeletal Muscle Stem Cells
21. Stem Cells and the Regenerating Heart
22. Cell Lineages and Stem Cells in the Embryonic Kidney
23. Adult Liver Stem Cells
24. Pancreatic Stem Cells
25. Stem Cells in the Gastrointestinal Tract

IV: Methods

26. Induced Pluripotent Stem Cells
27. Embryonic Stem Cells: Derivation and Properties
28. Isolation and Maintenance of Murine Embryonic Stem Cells
29. Approaches for Derivation and Maintenance of Human Embryonic Stem Cells
30. Derivation and Differentiation of Human Embryonic Germ Cells
31. Genomic Reprogramming

V: Applications

32. Neural Stem Cells – Therapeutic Applications in Neurodegenerative Diseases
33. Adult Progenitor Cells as a Potential Treatment for Diabetes
34. Burns and Skin Ulcers
35. Stem Cells and Heart Disease
36. Stem Cells for the Treatment of Muscular Dystrophy
37. Cell Therapy for Liver Disease
38. Orthopedic Applications of Stem Cells
39. Embryonic Stem Cells in Tissue Engineering

VI: Regulation and Ethics

40. Ethical Considerations
41. Overview of the FDA Regulatory Process
42. It’s Not about Curiosity, It’s about Cures

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