Fundamentals of Cancer Epidemiology 2nd Edition by Phillip Nasca, Harris Pastides – Ebook PDF Instant Download/Delivery: 076373618X , 978-0763736187
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Product details:
ISBN 10: 076373618X
ISBN 13: 978-0763736187
Author: Phillip Nasca, Harris Pastides
Fundamentals of Cancer Epidemiology 2nd Table of contents:
Chapter 1 The Descriptive Epidemiology of Cancer
Sources of Information
The Magnitude of Cancer
Geographic Variation of Cancer
Cancer in Developing Nations
Migrant Studies
Summary
Chapter 2 Basic Terminology
Pathologic Features of Cancer
Benign and Malignant Neoplasms
Metastasis
Angiogenesis
Cancer Diagnosis
Molecular Pathology
Cancer Staging
Classification of Neoplasms
Case Identification Problems and Epidemiological Research
Summary
Chapter 3 Biology of Normal Cells
The Eukaryotic Cell
Gene Expression in Normal Eukaryotic Cells
DNA Replication and Cell Division in Normal Cells
Summary
Chapter 4 Biology of Cancer Cells
Defects in Gene Expression
Defects in DNA Replication
Factors That Cause Carcinogenic Mutations
Inherited Mutations
Tumor Promoters
Summary
Chapter 5 Laboratory Experimental Studies
Animal Testing
Short-Term Testing
Structure-Activity Relationships
Classification of Substances as Carcinogens
Summary
Chapter 6 Biomarkers and Epidemiological Studies of Cancer
Types of Biomarkers
Internal Dose
Biologically Effective Dose
Preclinical Biologic Effect
Markers of Susceptibility
Some Methodological Issues
Interpretation of Findings
Gene-Environment Interactions
Biological Specimen Banks
Ethical Issues
Summary
Chapter 7 Epidemiological Studies of Genetic Factors for Cancer
Fundamental Concepts of Human Genetics
High-Penetrance versus Low-Penetrance Genetic Factors
Basic DNA Analysis Techniques in Molecular Epidemiological Studies
Epidemiological Approaches to the Study of Cancer-Related Genetic Factors
Summary
Chapter 8 Occupation and Cancer
Landmarks in Occupational Cancer Research
The Magnitude of the Problem of Occupational Carcinogenesis
Sources of Information about Occupational Cancer Risks
The IARC Classification Scheme
The Use of Epidemiology in Identifying Occupational Cancer Risks
Biological Monitoring
Medical Surveillance
Cancer Clusters
Occupational Carcinogenesis in Developing Countries
Summary
Chapter 9 Tobacco and Cancer
Tobacco Use in the United States from 1880 to 1995
Health and Economic Impacts of Cigarette Smoking
Mutagens and Carcinogens in Tobacco Smoke
Measuring Human Exposure to Tobacco Products
Epidemiological Studies
Environmental Tobacco Smoke
Smokeless Tobacco
Interactions between Tobacco and Other Environmental Exposures
2002 IARC Review of Tobacco and Cancer
Impact of Tobacco on Global Health
Summary
Chapter 10 Alcohol and Cancer
Alcohol Consumption Patterns and the Economic Costs of Alcohol Abuse
Scientific Evidence Linking Alcohol and Selected Cancers
Measuring Alcohol Exposure in Epidemiological Studies
Alcohol and Cancers of the Oral Cavity and Pharynx, Esophagus, and Larynx
Alcohol and Cancers of the Lower Gastrointestinal Tract
Alcohol and Breast Cancer
Prevention
Summary
Chapter 11 Ionizing, Nonionizing, and Solar Radiation and Cancer
What Is Radiation?
Ionizing Radiation
Electromagnetic Radiation
Solar Radiation
Summary
Chapter 12 Infectious Agents and Cancer
Viruses and Cancer: General Principles
Hepatocellular Carcinoma and Hepatitis Viruses B and C
Human Papillomaviruses
Epstein-Barr Virus
Human T-Cell Lymphotropic Virus and Adult T-Cell Leukemias
Helicobacter pylori Infection and Cancer
Parasites and Cancer
Summary
Chapter 13 Immunity and Cancer Risk
Inborn Immunodeficiency Disorders
Induced Immunosuppression
Possible Biologic Mechanisms
Other Cancers
Preventing Cancer in Immunosuppressed Individuals
Thymectomy, Splenectomy, and Tonsillectomy
Immunostimulation
Summary
Chapter 14 Endogenous Hormones and Cancer
Breast Cancer
Application of the Etiologic Model
Summary
Chapter 15 Exogenous Hormones and Cancer
Combined Oral Contraceptives
Postmenopausal Hormones
Tamoxifen and Raloxifene
Diethylstilbestrol
Summary
Chapter 16 Diet and Cancer
An Overview of Foods and Nutrients
Types of Studies Used to Investigate the Relationship between Diet and Cancer
Methods for Determining Dietary Intake
Epidemiological Evidence Regarding Diet and Cancer
Diet and Cancer: A Global Perspective
Decreasing the Burden of Cancer through Dietary Modification
Summary
Chapter 17 Childhood Cancer
Cancers That Occur among Children
Incidence Patterns
Cancer Survival
Framework for Understanding Etiology of Childhood Cancers
Etiology
Study Design Issues
Summary
Chapter 18 Cancer Screening
Basic Concepts
Study Designs
Screening for Five Major Cancers
Screening Practices in the General Population
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