Management of Soft Tissue Sarcoma 2nd Edition by Murray Brennan, Cristina Antonescu, Kaled Alektiar, Robert Maki – Ebook PDF Instant Download/Delivery: 3319419048 , 978-3319419046
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ISBN 10: 3319419048
ISBN 13: 978-3319419046
Author: Murray Brennan, Cristina Antonescu, Kaled Alektiar, Robert Maki
Management of Soft Tissue Sarcoma 2nd Table of contents:
Part I: Introduction
Chapter 1: General Description
1.1 Introduction
1.2 Incidence and Prevalence
1.3 Predisposing and Genetic Factors
References
Chapter 2: Natural History: Importance of Size, Site, Histopathology
2.1 Natural History
2.2 Influence of Site
2.3 Staging
2.4 Staging of Retroperitoneal and Visceral Sarcoma
2.5 Prognostic Factors for Extremity and Superficial Soft Tissue Sarcoma
2.6 Disease-Specific Survival
2.7 Prognostic Factors for Survival Following Local Recurrence of Extremity Sarcoma
2.8 AJCC Staging
2.9 Prognostic Factors—Nomograms
References
Chapter 3: General Statement as to Efficacy of Surgery, Chemotherapy, Radiation Therapy, and Imm
3.1 Extent of Primary Surgery
3.2 Surgical Treatment of Local Recurrence
3.3 Diagnostic Imaging
3.4 Surgery for Metastatic Disease
3.4.1 Pulmonary Metastasis
3.4.1.1 The Role of Pulmonary Metastatic Resection
3.4.2 Surgery and Management of Sarcoma Liver Metastasis
3.5 Radiation Therapy
3.5.1 Adjuvant Radiation Therapy
3.5.2 Types of Radiation Therapy
3.5.3 Dose/Volume of Radiation Therapy
3.5.4 Morbidity of Adjuvant Radiation Therapy
3.5.5 Definitive Radiation Therapy
3.6 Adjuvant and Neoadjuvant Chemotherapy for Soft Tissue Sarcomas
3.6.1 Sarcomas More Common in Adults
3.6.2 Larger Randomized Studies
3.6.3 Selected Meta-analyses of Randomized Trials of Adjuvant Chemotherapy
3.6.4 Adjuvant Therapy for GIST
3.6.5 Sarcomas More Common in the Pediatric Setting
3.7 Brief Comments Regarding Chemotherapy for Metastatic Soft Tissue Sarcoma
3.8 Special Techniques for Primary and Locally Recurrent Disease
3.8.1 Intra-arterial Chemotherapy
3.8.2 Limb Perfusion and Hyperthermia
3.9 Immunotherapy for Sarcomas
References
Part II: Management by Histopathology
Chapter 4: Gastrointestinal Stromal Tumors
4.1 Imaging
4.2 Familial GIST
4.3 Natural History
4.4 Diagnosis, Molecular Pathology
4.5 Treatment
4.6 Adjuvant Imatinib for Primary GIST
4.7 Neoadjuvant Therapy for Primary Disease Not Amenable to Surgery
4.8 Treatment of Recurrence
4.9 First line Imatinib For Metastatic GIST
4.10 Dose Intensity Over Time
4.11 Imatinib Pharmacokinetics
4.12 Second Line Sunitinib for Imatinib-Resistant Metastatic GIST
4.13 Regorafenib in Third Line for Metastatic GIST
4.14 Other Tyrosine Kinase Inhibitors for Metastatic GIST Failing Imatinib and Sunitinib
4.15 Newer Agents for GIST
References
Chapter 5: Liposarcoma
5.1 Imaging
5.2 Diagnosis
5.3 Treatment
5.4 Radiation Therapy for Liposarcoma
5.5 Systemic Therapy: General Considerations
5.6 Adjuvant Therapy
5.7 Treatment of Metastatic Disease
5.8 Outcomes
5.9 Outcome Following Metastasis
References
Chapter 6: Leiomyosarcoma
6.1 Imaging
6.2 Diagnosis, Molecular Pathology
6.3 Primary Treatment
6.4 Radiation Therapy
6.5 Systemic Therapy
6.5.1 Adjuvant Chemotherapy for Leiomyosarcoma
6.6 Outcomes After Primary Therapy
6.7 Patterns of Recurrence
6.7.1 Treatment of Recurrence
6.8 Metastatic Disease
References
Chapter 7: Undifferentiated Pleomorphic Sarcoma (UPS) (Malignant Fibrous Histiocytoma (MFH) and Myx
7.1 Imaging
7.2 Diagnosis, Molecular Pathology
7.3 Natural History
7.4 Treatment
7.5 Radiation Therapy
7.6 Metastatic Disease
7.7 Adjuvant Chemotherapy
7.8 Outcome
References
Chapter 8: Synovial Sarcoma
8.1 Imaging
8.2 Diagnosis, Molecular Pathology
8.3 Treatment
8.4 Radiation Therapy
8.5 Chemotherapy
8.6 Treatment of Recurrence
8.6.1 Local Recurrence
8.7 Systemic Treatment
8.8 Outcome
References
Chapter 9: Malignant Peripheral Nerve Sheath Tumor (MPNST) and Triton Tumor
9.1 Presentation
9.2 Imaging
9.3 Diagnosis, Pathology
9.4 Neurofibromatosis Type 1 and Outcome
9.5 Treatment
9.6 Radiation Therapy
9.7 Chemotherapy for MPNST
9.8 Outcome
References
Chapter 10: Desmoid Tumor/Deep-Seated Fibromatosis (Desmoid-Type Fibromatosis)
10.1 Clinical Presentation
10.2 Imaging
10.3 Diagnosis, Molecular Pathology
10.4 Natural History
10.5 Treatment
10.6 Treatment of Recurrence
10.7 Systemic Therapy
10.8 Treatment by Observation
10.9 Radiation Therapy
10.10 Patterns of Failure
10.11 Outcome
References
Chapter 11: Solitary Fibrous Tumor/Hemangiopericytoma
11.1 Doege–Potter Syndrome
11.2 Primary Therapy
11.3 Systemic Therapy for Metastatic Disease
11.4 Outcome
References
Chapter 12: Fibrosarcoma and Its Variants
12.1 Outcome
12.2 Dermatofibrosarcoma Protuberans
12.2.1 Outcome
12.3 Low-Grade Fibromyxoid Sarcoma (Also Termed Evans Tumor)
12.3.1 Outcome
12.4 Sclerosing Epithelioid Fibrosarcoma
12.5 Inflammatory Myofibroblastic Tumor
12.6 Infantile Fibrosarcoma
12.7 Myxoinflammatory Fibroblastic Sarcoma/Inflammatory Myxohyaline Tumor of Distal Extremities
12.8 Adult-Type Fibrosarcoma
References
Chapter 13: Vascular Sarcomas
13.1 Epithelioid Hemangioendothelioma
13.2 Angiosarcoma/Lymphangiosarcoma
13.3 Outcome
13.4 Kaposi Sarcoma
References
Chapter 14: Epithelioid Sarcoma
14.1 Outcome
References
Chapter 15: Sarcomas More Common in Children
15.1 Soft Tissue Sarcomas More Commonly Observed in Pediatric Patients
15.2 Ewing Sarcoma Family of Tumors
15.3 Demographics
15.4 Primary Therapy
15.5 Adjuvant Chemotherapy
15.6 High-Dose Systemic Therapy for Metastatic Disease
15.7 Standard Cytotoxic Chemotherapy After Disease Relapse
15.8 Investigational Approaches
15.9 Ewing Sarcoma-Like Small Blue Round Cell Tumors
15.10 Rhabdomyosarcoma
15.11 Demographics
15.12 Molecular Biology
15.13 Risk Stratification
15.14 Staging
15.15 Imaging
15.16 Primary Therapy
15.17 Chemotherapy for Metastatic Disease
15.18 Mesenchymal Chondrosarcoma
15.19 Embryonal Sarcoma
References
Chapter 16: Radiation-Induced Sarcoma
References
Chapter 17: Alveolar Soft Part Sarcoma
17.1 Imaging
17.2 Diagnosis, Molecular Pathology
17.3 Primary Treatment
17.4 Treatment of Metastatic Disease
17.5 Outcome
References
Chapter 18: Clear Cell Sarcoma/Melanoma of Soft Parts
18.1 Imaging
18.2 Diagnosis, Molecular Pathology
18.3 Treatment
18.4 Outcome
References
Chapter 19: Desmoplastic Small Round Cell Tumor
19.1 Imaging
19.2 Diagnosis
19.3 Treatment
19.4 Outcome
References
Chapter 20: Extraskeletal Myxoid Chondrosarcoma
20.1 Imaging
20.2 Diagnosis
20.3 Treatment
20.4 Outcome
References
Chapter 21: Other Uterine Sarcomas
21.1 Low Grade Endometrial Stromal Sarcoma
21.1.1 Diagnosis
21.1.2 Treatment
21.1.3 Outcome
21.2 High Grade Endometrial Stromal Sarcoma
21.2.1 Outcome
21.3 Undifferentiated Uterine Sarcoma (UUS)
21.4 PEComas
21.5 Uterine Carcinosarcomas and Other Malignant Mixed Müllerian Tumors
21.6 Outcome
References
Chapter 22: Extraskeletal Osteogenic Sarcoma
22.1 Imaging
22.2 Diagnosis
22.3 Treatment
22.4 Outcome
References
Chapter 23: Sustentacular Tumors of Lymph Tissue
23.1 Follicular Dendritic Cell Tumor and Interdigitating Reticulum Cell Tumor
23.2 True Histiocytic Sarcoma
23.3 Langerhans Cell Tumors
23.4 Outcome
References
Chapter 24: Uncommon/Unique Sites
24.1 Heart and Great Vessels
24.2 Primary Sarcomas of the Breast
24.2.1 Phyllodes Tumor
24.2.1.1 Diagnosis
24.2.1.2 Outcome
24.3 Head and Neck
24.3.1 Treatment
24.4 Primary Sarcomas of the Mediastinum
24.5 Liver
References
Part III: Benign and Less Aggressive Lesions
Chapter 25: Mostly Benign/Rarely Metastasizing
25.1 Ossifying Fibromyxoid Tumor
25.2 Perivascular Epithelioid Cell Tumor (PEComa) and Related Entities, Lymphangioleiomyomatosis, A
25.3 Therapy
25.4 Giant Cell Tumor of Tendon Sheath/Pigmented Villonodular Synovitis
25.5 Myoepithelial Tumors of Soft Tissue
25.6 Glomus Tumor
References
Chapter 26: Selected Benign Tumors
26.1 Lipoma
26.2 Lipomatosis
26.3 Lipoblastoma/Lipoblastomatosis
26.4 Angiolipomas
26.5 Angiomyolipoma
26.6 Angiomyelolipoma
26.7 Hibernoma
26.8 Elastofibroma
26.9 Granular Cell Tumors
26.10 Hemangioma
26.11 Leiomyoma
26.12 Schwannoma
26.13 Neurofibroma
26.14 Myxoma
26.15 Angiomyxoma
26.16 Angiofibroma
References
Chapter 27: Reactive Lesions
27.1 Myositis Ossificans
27.2 Nodular Fasciitis
27.3 Sarcoma Masquerade
References
Index
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Tags: Murray Brennan, Cristina Antonescu, Kaled Alektiar, Robert Maki, Soft Tissue


