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Molecular Pathology The Molecular Basis of Human Disease 2th edition by William Coleman, Gregory Tsongalis 0128027614 9780128027615

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ISBN 10: 0128027614

ISBN 13: 9780128027615

Author: William B. Coleman, Gregory J. Tsongalis

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine.

The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine.  The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states.

  • Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease
  • Explains the practice of “molecular medicine” and the translational aspects of molecular pathology
  • Teaches from the perspective of “integrative systems biology”
  • Enhanced digital version included with purchase

Molecular Pathology The Molecular Basis of Human Disease 2th Table of contents:

  1. Molecular Mechanisms of Cell Death
  2. Disease Pathogenesis Caused by Acute and Chronic Inflammation
  3. Infection and Host Immune Response
  4. Neoplasia (Tumor Formation)
  5. Fundamental Concepts in Human Molecular Genetics
  6. The Human Genome and Its Role in Understanding Disease
  7. The Human Transcriptome’s Impact on Disease Comprehension
  8. The Human Epigenome’s Influence on Disease Insights
  9. Clinical Proteomics and Molecular Pathology
  10. Integrative Systems Biology and Disease Understanding
  11. Clinical Pathology: Human Disease Descriptions
  12. Molecular Pathogenesis: Advancements for Better Disease Treatment
  13. Bioinformatics Approach to Integrating Molecular and Cellular Pathogenesis
  14. Cardiovascular Disease: Molecular Foundations
  15. Hemostatic and Thrombotic Disorders: Molecular Insights
  16. Lymphoid and Myeloid Diseases: Molecular Basis
  17. Immune System Diseases: Molecular Mechanisms
  18. Pulmonary Disease at the Molecular Level
  19. Gastrointestinal Tract Disorders: Molecular Foundations
  20. Liver Disease: Molecular Basis
  21. Exocrine Pancreas Diseases: Molecular Understanding
  22. Endocrine System Disorders: Molecular Mechanisms
  23. Gynecologic Diseases: Molecular Foundations
  24. Kidney Disease: Molecular Insights
  25. Prostate Cancer: Molecular Pathogenesis
  26. Breast Cancer: Molecular Biology
  27. Skin Diseases: Molecular Foundations
  28. Bone Diseases: Molecular Mechanisms
  29. Nervous System Disorders: Molecular Basis
  30. Molecular Diagnosis in Human Disease
  31. Clinical Laboratory Molecular Assessment of Disease
  32. Pharmacogenomics and Personalized Medicine in Disease Treatment

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