The Molecules of Life Physical and Chemical Principles 1st edition by John Kuriyan, Boyana Konforti, David Wemmer – Ebook PDF Instant Download/Delivery: 1000363147 , 9781000363142
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Product details:
ISBN 10: 1000363147
ISBN 13: 9781000363142
Author: John Kuriyan, Boyana Konforti, David Wemmer
This textbook provides an integrated physical and biochemical foundation for undergraduate students majoring in biology or health sciences. It is particularly suitable for students planning to enter the pharmaceutical industry. This new generation of molecular biologists and biochemists will harness the tools and insights of physics and chemistry to exploit the emergence of genomics and systems-level information in biology, and will shape the future of medicine.
The Molecules of Life Physical and Chemical Principles 1st Table of contents:
1. Introduction to Biological Molecules
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Overview of Biological Macromolecules
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Importance of Molecular Interactions in Biology
2. Principles of Molecular Interactions
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Noncovalent Forces in Molecular Stability
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Hydrogen Bonds
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Ionic Interactions
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Van der Waals Forces
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3. Structure of Nucleic Acids
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DNA Structure and Double Helical Formation
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Role of Nucleotides in DNA and RNA
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RNA Structure and Functional Variations
4. Protein Structure and Function
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Proteins as Polymers of Amino Acids
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Folding of Proteins and Hydrophobic Interactions
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Secondary Structural Elements: α Helices and β Sheets
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Structural Variations and Functional Versatility of Proteins
5. Genetic Information Transfer and Expression
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DNA Replication Process
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Transcription and RNA Synthesis
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Translation and Protein Synthesis
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Role of mRNA, tRNA, and rRNA
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Mechanisms of RNA Splicing
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6. Molecular Mechanisms in Protein Synthesis
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Transfer RNAs and Their Role in Translation
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Conservation of Replication, Transcription, and Translation Across Organisms
7. Glycan and Lipid Interactions
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Glycans and Their Role in Cellular Recognition
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Lipid Interactions in Membrane Dynamics
8. Thermodynamics of Molecular Interactions
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Free Energy and Chemical Potential
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Enzyme Catalysis Principles
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Factors Influencing Enzyme Activity
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Effects of Inhibitors and Allosteric Regulation
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9. Fidelity in DNA and Protein Synthesis
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Mechanisms Ensuring Accurate DNA Replication
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Protein Synthesis Accuracy and the Role of Quality Control
10. Conclusion
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Importance of Molecular Interactions in Cellular Integrity and Function
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