Neuroglia 3rd Edition by Bruce Ransom, Helmut Kettenmann – Ebook PDF Instant Download/Delivery: 0199794731 , 9780199794737
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ISBN 10: 0199794731
ISBN 13: 9780199794737
Author: Bruce Ransom, Helmut Kettenmann
Neuroglia, the third edition, is the long-awaited revision of the most highly regarded reference volume on glial cells. This indispensable edition has been completely revised, greatly enlarged, and enhanced with four-color figures throughout, all in response to the tremendous amount of new information that has accumulated since the previous edition seven years ago. Glial cells are, without doubt, the new stars in the neuroscience and neurology communities. Neglected in research for years, it is now evident that the brain only functions in a concerted action of all the cells, namely glia and neurons.Seventy one chapters comprehensively discuss virtually every aspect of normal glial cell anatomy, physiology, biochemistry and function, and consider the central roles of these cells in neurological diseases including stroke, Alzheimer disease, multiple sclerosis, Parkinson’s disease, neuropathy, and psychiatric conditions. More than 20 new chapters have been added to accommodate the unprecedented growth of knowledge about the basic biology of glia and the sophisticated manner in which they partner with neurons in the course of normal brain function. Lavishly illustrated and meticulously edited, the third edition remains the most convenient and maximally useful reference available. This new edition is an essential reference for both newcomers to the field as well as established investigators. Neuroglia belongs on every neuroscientist’s bookshelf and will be a great asset for educators and neurological clinicians as well.
Neuroglia 3rd Table of contents:
SECTION 1 PROPERTIES OF NEUROGLIAL CELLS
Evolution of Glial Cells: Insights from Non-Mammalian Glia
1. Evolution of Glial Cells
2. Invertebrate Glia
3. Nonmammalian Vertebrate Glia
Morphology, Ultrastructure, and Identification
4. Astrocytes and Ependymal Glia
5. Radial Glial Cells
6. Structure and Function of Oligodendrocytes
7. Schwann Cells and Myelin
8. Microglial Cells
9. Pericytes of the Central Nervous System
10. NG2 Cells (Polydendrocytes)
11. Glial Cells in Autonomic and Sensory Ganglia
Lineage and Development
12. Astrocyte Development
13. Lineage and Development: Oligodendrocytes
14. The Schwann Cell Lineage: Cellular Transitions During Development and After Injury
15. Microglia Lineage and Development
Physiological Properties
16. Physiology of Astrocytes: Ion Channels and Ion Transporters
17. Release of Gliotransmitters and Transmitter Receptors in Astrocytes
18. Storage and Release of Nontransmitter Signaling Molecules from Macroglia
19. Physiology of Microglia
20. Physiology of Oligodendrocytes
21. Physiological Properties of NG2[Sup(+)] Glial Cells
22. Cytokine, Chemokine, and Growth Factor Receptors and Signaling
23. Lipids, Lipid Mediators, and Other Signaling Molecules
24. Gap Junctions and Hemichannels
25. Purinergic Mechanisms in Glial Cells
26. Calcium Signaling in Neuroglia
27. The Central Role of Astrocytes in Neuroenergetics
Genomic Profiles
28. The Astrocyte Transcriptome
29. Gene Expression Patterns of Oligodendrocyte Progenitor Cells and Oligodendroglia
SECTION 2 FUNCTIONS OF NEUROGLIAL CELLS
Astrocytes
30. Neurogenesis and Outer Subventricular Zone Radial Glial Cells
31. Glial Control of Synaptogenesis
32. Neuron Migration and Axon Guidance
33. The Role of Glia in the Formation and Function of the Blood-Brain Barrier
34. Control of the Extracellular Ionic Environment and Volume
35. Amino Acid Neurotransmitter Synthesis and Removal
36. Glycogen and Energy Metabolism
37. Astrocyte Regulation of Neurovascular Control
38. Astrocytes: Modulation of Synaptic Function and Network Activity
39. Astrocytic Modulation of Mammalian Synapses: Circuits and Behaviors
40. Adult Neurogenesis
41. Modulation of Neuroendocrine Systems
Oligodendrocytes/Schwann Cells
42. Myelin, Impulse Conduction, and the Pathophysiology of Demyelination
43. Transcription Factors in Myelinating Cells
44. Factors Controlling Myelin Formation
45. Regulation of Myelination by Functional Activity
46. Iron and Glia
Microglia
47. Role of Microglia in the Normal Brain
48. Factors Controlling Microglial Activation
49. Roles of Activated Microglia
50. Immune Functions of Microglia
SECTION 3 ROLE OF GLIAL CELLS IN DISEASE
Mechanisms of Glial Injury
51. Astrocyte Responses to Central Nervous System Injury and Disease
52. Metabolic Injury of Oligodendrocytes and Myelin
53. Interaction of Microglia with Neurons and Astrocytes Under Lesioned Neuronal Conditions
54. Schwann Cells and Injury
Recovery of Neural Function
55. Nerve Regeneration in the Peripheral Nervous System
56. Nerve Fiber Regeneration in the Central Nervous System of Higher Vertebrates
57. Glial Cell Transplantation for Central Nervous System Repair
Ischemia
58. Focal Cerebral Ischemia: The Multifaceted Role of Glial Cells
Gliomas
59. Malignant Glioma
60. Glial Tumors in Neurofibromatosis and Tuberous Sclerosis Complex
Demyelinating Diseases
61. Multiple Sclerosis
62. Genetic Mutations Affecting Myelin Formation
Neurodegenerative Diseases
63. Amyotrophic Lateral Sclerosis
64. Alzheimer Disease
65. Huntington Disease, Parkinson Disease, and Other Neurodegenerative Diseases
Infectious Diseases
66. Glia in Bacterial and Viral Central Nervous System Infections
Miscellaneous Diseases
67. Neuroglia in Hepatic Encephalopathy
68. Microglia and Pain
69. Genetic Disorders Affecting Astrocytes
70. Epilepsy
71. Psychiatric Disorders
Index
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