Principles of Stem Cell Biology and Cancer Future Applications and Therapeutics 2015 1st Edition by Tarik Regad, Thomas Sayers, Robert Rees ISBN 0128141483 9781118670620

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ISBN 10: 0128141483
ISBN 13: 9781118670620
Author: Tarik Regad, Thomas Sayers, Robert Rees

Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem Cell Biology and Cancer brings together original contributions from international experts in the field to present the very latest information linking stem cell biology and cancer. Divided into two parts, the book begins with a detailed introduction to stem cell biology with a focus on the characterization of these cells, progress that has been made in their identification, as well as future therapeutic applications of stem cells. The second part focuses on cancer stem cells and their role in cancer development, progression and chemo-resistance. This section of the book includes an overview of recent progress concerning therapies targeting cancer stem cells. Features: An authoritative introduction to the link between stem cell biology and cancer. Includes contributions from leading international experts in the field. Well-illustrated with full colour figures throughout. This book will prove an invaluable resource for basic and applied researchers and clinicians working on the development of new cancer treatments and therapies, providing a timely publication of high quality reviews outlining the current progress and exciting future possibilities for stem cell research.

Principles of Stem Cell Biology and Cancer Future Applications and Therapeutics 2015 1st Table of contents:

Part I Stem Cells 1

1 Isolation and Characterization of Human Embryonic Stem Cells and Future Applications in Tissue Engineering Therapies 

2 Epigenetics, Stem Cell Pluripotency and Differentiation 

3 Stem Cell Niche and Microenvironment 

4 Haematopoietic Stem Cells in Therapy 

5 Isolation and Identification of Neural Stem/Progenitor Cells

Part II Cancer Stem Cells 101

6 The Role of Epithelial–Mesenchymal Transition in Cancer Metastasis

7 Regulation of Breast Cancer Stem Cells by Mesenchymal Stem Cells in the Metastatic Niche 

8 Isolation and Identification of Neural Cancer Stem/Progenitor Cells 

9 Colon Stem Cells in Colorectal Cancer 

10 Prostate Cancer and Prostate Cancer Stem Cells 

11 Stem Cells and Pancreatic Cancer

12 NANOG in Cancer Development 

13 Liver Cancer Stem Cells and Hepatocarcinogenesis

14 Basic Science of Liver Cancer Stem Cells and Hepatocarcinogenesis 

15 Cancer Stem Cell Biomarkers 

16 Interatomic Analysis of the Stem Cell Marker NANOG in a Prostate Cancer Setting

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