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ISBN 10: 1464178931
ISBN 13: 9781464178931
Author: Valerie Knopik
With its clear and concise presentation, Behavioral Genetics, 7th edition introduces students to the field’s underlying principles, defining experiments, ongoing controversies, and most recent discoveries. The text provides students with an understanding of heredity, it’s DNA basis, the methods used to discover genetic influence on behavior and identify specific genes. It then examines what is known about genetic influence on cognitive ability, psychopathology, substance abuse, personality, health psychology, and aging. Finally it looks ate the future of the field of Behavioral Genetics and area where some of the most exciting development in the Behavioral sciences are being made.
Behavioral Genetics 7th Table of contents:
CHAPTER ONE: Overview
CHAPTER TWO: Historical Perspective
THE ERA OF DARWIN
Charles Darwin
Francis Galton
BOX 2.1 Francis Galton
PRE-MENDELIAN CONCEPTS OF HEREDITY AND VARIATION
Heredity
Variation
Summary
CHAPTER THREE: Mendel’s Laws and Beyond
MENDEL’S LAWS
Mendel’s First Law of Heredity
BOX 3.1 Gregor Mendel’s Luck
BOX 3.2 How Do We Know That 1 in 50 People Are Carriers for PKU?
Mendel’s Second Law of Heredity
BEYOND MENDEL’S LAWS
Complex Traits
Multiple-Gene Inheritance
Quantitative Genetics
BOX 3.3 Liability-Threshold Model of Disorders
The X-Chromosome: An Extension to Mendel’s Laws
Summary
CHAPTER FOUR: The Biological Basis of Heredity
DNA
BOX 4.1 The “Central Dogma” of Molecular Genetics
CHROMOSOMES
Summary
CHAPTER FIVE: Animal Models in Behavioral Genetics
QUANTITATIVE GENETIC EXPERIMENTS TO INVESTIGATE ANIMAL BEHAVIOR
Selection Studies
Inbred Strain Studies
ANIMAL STUDIES FOR IDENTIFYING GENES AND GENE FUNCTIONS
Creating Mutations
Quantitative Trait Loci
Synteny Homology
Summary
CHAPTER SIX: Nature, Nurture, and Human Behavior
INVESTIGATING THE GENETICS OF HUMAN BEHAVIOR
Adoption Designs
BOX 6.1 The First Adoption Study of Schizophrenia
Twin Design
BOX 6.2 Issues in Adoption Studies
BOX 6.3 The Twin Method
Combination
Summary
CHAPTER SEVEN: Estimating Genetic and Environmental Influences
HERITABILITY
INTERPRETING HERITABILITY
BOX 7.1 Estimating Heritability Directly from DNA
ENVIRONMENTALITY
Shared Environment
Nonshared Environment
Estimating Shared and Nonshared Environmental Influences
Identifying Specific Nonshared Environment
Identifying Specific Nonshared Environment That Predicts Behavioral Outcomes
MULTIVARIATE ANALYSIS
Summary
CHAPTER EIGHT: The Interplay between Genes and Environment
BEYOND HERITABILITY
GENOTYPE-ENVIRONMENT CORRELATION
The Nature of Nurture
Three Types of Genotype-Environment Correlation
Three Methods to Detect Genotype-Environment Correlation
Implications
GENOTYPE-ENVIRONMENT INTERACTION
Animal Models
Adoption Studies
Twin Studies
DNA
Summary
CHAPTER NINE: Identifying Genes
MUTATIONS
Expanded Triplet Repeats
DETECTING POLYMORPHISMS
BOX 9.1 DNA Markers
HUMAN BEHAVIOR
Linkage: Single-Gene Disorders
Linkage: Complex Disorders
Association: Candidate Genes
BOX 9.2 Affected Sib-Pair Linkage Design
Association: Genomewide
BOX 9.3 SNP Microarrays
Summary
CHAPTER TEN: Pathways between Genes and Behavior
GENE EXPRESSION AND THE ROLE OF EPIGENETICS
BOX 10.1 Levels of Analysis
THE TRANSCRIPTOME: GENE EXPRESSION THROUGHOUT THE GENOME
Gene Expression Profiles: RNA Microarrays and Sequence-Based Approaches
Gene Expression and Genetics
Gene Expression as a Biological Basis for Environmental Influence
THE PROTEOME: PROTEINS CODED THROUGHOUT THE TRANSCRIPTOME
The Brain
BOX 10.2 Endophenotypes
Learning and Memory
Neuroimaging
Summary
CHAPTER ELEVEN: Cognitive Abilities
ANIMAL RESEARCH
GENERAL COGNITIVE ABILITY
SPECIFIC COGNITIVE ABILITIES
NEUROCOGNITIVE MEASURES OF COGNITIVE ABILITIES
SCHOOL ACHIEVEMENT
THREE SPECIAL GENETIC FINDINGS ABOUT COGNITIVE ABILITIES
Heritability Increases During Development
Assortative Mating Is Substantial
The Same Genes Affect Diverse Cognitive and Learning Abilities
IDENTIFYING GENES
Summary
CHAPTER TWELVE: Cognitive Disabilities
GENERAL COGNITIVE DISABILITY: QUANTITATIVE GENETICS
GENERAL COGNITIVE DISABILITY: SINGLE-GENE DISORDERS
Phenylketonuria
Fragile X Syndrome
Rett Syndrome
Other Single-Gene Disorders
GENERAL COGNITIVE DISABILITY: CHROMOSOMAL ABNORMALITIES
Down Syndrome
Sex Chromosome Abnormalities
Small Chromosomal Deletions
SPECIFIC COGNITIVE DISABILITIES
Reading Disability
Communication Disorders
Mathematics Disability
Comorbidity among Specific Cognitive Disabilities
Summary
CHAPTER THIRTEEN: Schizophrenia
FAMILY STUDIES
BOX 13.1 The Beginnings of Psychiatric Genetics: Bethlem Royal and Maudsley Hospitals
TWIN STUDIES
ADOPTION STUDIES
SCHIZOPHRENIA OR SCHIZOPHRENIAS?
IDENTIFYING GENES
Summary
CHAPTER FOURTEEN: Other Adult Psychopathology
MOOD DISORDERS
Family Studies
Twin Studies
Adoption Studies
SNP-Based Heritability
Identifying Genes
ANXIETY DISORDERS
OTHER DISORDERS
CO-OCCURRENCE OF DISORDERS
Identifying Genes
Summary
CHAPTER FIFTEEN: Developmental Psychopathology
AUTISM
Family and Twin Studies
Identifying Genes
ATTENTION-DEFICIT/HYPERACTIVITY DISORDER
Twin Studies
Identifying Genes
DISRUPTIVE BEHAVIOR DISORDERS
ANXIETY DISORDERS
OTHER DISORDERS
OVERVIEW OF TWIN STUDIES OF CHILDHOOD DISORDERS
SNP-BASED HERITABILITY FINDINGS FOR CHILDHOOD DISORDERS
Summary
CHAPTER SIXTEEN: Personality and Personality Disorders
SELF-REPORT QUESTIONNAIRES
OTHER MEASURES OF PERSONALITY
OTHER FINDINGS
Situations
Development
Nature-Nurture Interplay
PERSONALITY AND SOCIAL PSYCHOLOGY
Relationships
Attitudes and Political Behavior
Behavioral Economics
PERSONALITY DISORDERS
Schizotypal Personality Disorder
Obsessive-Compulsive Personality Disorder
Antisocial Personality Disorder and Criminal Behavior
IDENTIFYING GENES
Summary
CHAPTER SEVENTEEN: Substance Use Disorders
ALCOHOL DEPENDENCE
Twin and Adoption Research on Alcohol-Related Phenotypes
Animal Research on Alcohol-Related Phenotypes
Molecular Genetic Research on Alcohol-Related Phenotypes
NICOTINE DEPENDENCE
Twin Research on Smoking-Related Phenotypes
Molecular Genetic Research on Smoking-Related Phenotypes
OTHER DRUGS
COMPLEXITIES OF STUDYING THE GENETICS OF SUBSTANCE USE
Summary
CHAPTER EIGHTEEN: Health Psychology
GENETICS AND HEALTH PSYCHOLOGY
Body Weight and Obesity
Subjective Well-Being and Health
HEALTH PSYCHOLOGY AND GENETIC COUNSELING
BOX 18.1 Genetic Counseling
Summary
CHAPTER NINETEEN: Aging
COGNITIVE AGING
General Cognitive Ability
Specific Cognitive Abilities
Dementia
Genes and Normal Cognitive Aging
HEALTH AND AGING
Physiological Functioning
Behavioral and Physical Functioning
Self-Rated Health
Molecular Genetics and Physical Health
LONGEVITY
Summary
CHAPTER TWENTY: The Future of Behavioral Genetics
QUANTITATIVE GENETICS
MOLECULAR GENETICS
IMPLICATIONS OF NATURE AND NURTURE
APPENDIX: Statistical Methods in Behavioral Genetics
1. INTRODUCTION
BOX A.1 Behavioral Genetic Interactive Modules
1.1 Variation and Covariation: Statistical Descriptions of Individual Differences
2. QUANTITATIVE GENETICS
2.1 The Biometric Model
2.2 Estimating Variance Components
3. MOLECULAR GENETICS
3.1 Linkage Analysis
3.2 Association Analysis
Websites
Glossary
References
Name Index
Subject Index
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